A Pilot Study Examining Feasibility and Initial Efficacy of Remotely Delivered Cognitive Adaptation Training.

Schizophrenia bulletin open Pub Date : 2023-10-01 eCollection Date: 2023-01-01 DOI:10.1093/schizbullopen/sgad028
Dawn I Velligan, Feiyu Li, Veronica Sebastian, Cory Kennedy, Jim Mintz
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Abstract

Cognitive Adaptation Training (CAT) is an evidence-based treatment that uses environmental supports including signs, text messages, checklists, smart pill containers, and the organization of belongings to bypass cognitive and motivational impairments and to cue adaptive behavior in the home or work environment. We developed and tested a remote version of CAT to make the treatment available more broadly. Because CAT is focused on working with the individual in their home environment to establish supports, CAT may not be as easy to translate into an effective virtual treatment as talk-therapies. Fifty-six members of managed care were assigned to or given their treatment preference for CAT or Remote CAT (R-CAT) for 6 months. In-person or virtual pill counts were conducted monthly and assessments of habit-formation, symptoms, functioning, and satisfaction were administered every 2 months by independent raters. Analyses using mixed models with repeated measures focused on pre-planned evaluations of within-group change. Adherence improved significantly in R-CAT, functioning improved significantly in CAT and both groups improved significantly on measures of habit-formation and symptoms across 6 months. Higher functioning individuals appeared to choose R-CAT. Satisfaction with treatment was very high in both groups. R-CAT appears to be a potentially effective treatment, particularly for medication follow-though. However, in contrast to decades of previous research, fewer than 20% of eligible Medicaid recipients agreed to participate in the study. This may have been due to recruitment during and immediately post-pandemic.

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远程认知适应训练可行性和初步效果的初步研究。
认知适应训练(CAT)是一种基于证据的治疗方法,它使用环境支持,包括标志、短信、检查表、智能药丸容器和物品的组织,以绕过认知和动机障碍,并提示在家庭或工作环境中的适应行为。我们开发并测试了CAT的远程版本,以使治疗更广泛地使用。由于CAT专注于在家庭环境中与个人合作以建立支持,因此CAT可能不像谈话疗法那样容易转化为有效的虚拟治疗。56名管理护理成员被分配到CAT或远程CAT(R-CAT),或给予他们6个月的治疗偏好。每月进行一次面对面或虚拟药丸计数,独立评分员每2个月对习惯形成、症状、功能和满意度进行一次评估。使用混合模型和重复测量的分析侧重于对组内变化的预先计划的评估。R-CAT的依从性显著改善,CAT的功能显著改善,两组在6个月内的习惯形成和症状测量方面都显著改善。功能较高的个体似乎选择R-CAT。两组患者对治疗的满意度都很高。R-CAT似乎是一种潜在的有效治疗方法,尤其是对药物治疗。然而,与几十年前的研究相比,只有不到20%的符合条件的医疗补助接受者同意参与这项研究。这可能是由于在疫情期间和疫情后立即进行的招聘。
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