Epidural steroid injections in treatment of chronic lower back pain caused by degenerative-dystrophic spine damage

M. Kvasnitskyi
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Abstract

Background. The high incidence of degenerative-dystrophic spine damage with the variability of research results on the effectiveness of epidural steroid injections for treatment of chronic lower back pain is an urgent issue regarding treatment of this pain with epidural steroid injections only. Objective. The aim of the study is to improve the effectiveness of treatment of chronic lower back pain caused by degenerative spine damage with monotherapy – epidural steroid injections only. Material and methods. The early and long-term treatment outcomes with epidural steroid injections only of 120 patients with chronic lower back pain were analysed. The control group consisted of 36 patients with lower back pain treated conservatively. The results of treatment were assessed by the dynamics of pain regression using the visual analog scale (VAS), as well as the functional status by the Oswestry index. The assessment was performed three times: before treatment, after treatment and six months after it. Results. In the early post-treatment period, reliable results of treatment of chronic lower lumbar pain was evidenced in both the main and control groups. There was no significant difference in treatment outcomes between these groups in the early period, although both the Oswestry index and the VAS by the Student’s T-test showed that the differences were in favour of the main group. There was a significant difference in long-term treatment outcomes between the main and control groups both by the Oswestry index and the VAS in favour of monotherapy with epidural steroid injections. Conclusions. The study proved a high effectiveness of monotherapy with epidural steroid injections for chronic lower back pain caused by degenerative-dystrophic spine damage.
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硬膜外类固醇注射治疗退行性营养不良性脊柱损伤引起的慢性下背痛
背景退行性营养不良性脊椎损伤的发病率很高,硬膜外类固醇注射治疗慢性下背痛的有效性研究结果也存在差异,这是仅用硬膜外类固醇注射液治疗这种疼痛的一个紧迫问题。客观的该研究的目的是提高单一疗法(仅硬膜外类固醇注射)治疗退行性脊椎损伤引起的慢性下背痛的有效性。材料和方法。对120例慢性下背痛患者硬膜外注射类固醇的早期和长期治疗结果进行了分析。对照组包括36例保守治疗的下背痛患者。使用视觉模拟量表(VAS)通过疼痛回归动力学评估治疗结果,并通过Oswestry指数评估功能状态。评估分三次进行:治疗前、治疗后和治疗后6个月。在治疗后的早期,主要组和对照组都证明了慢性下腰部疼痛的治疗效果可靠。早期,这些组之间的治疗结果没有显著差异,尽管Oswestry指数和Student’s T检验的VAS均显示差异有利于主要组。在Oswestry指数和VAS方面,主要组和对照组的长期治疗结果存在显著差异,有利于硬膜外类固醇注射的单一治疗。结论。该研究证明硬膜外类固醇注射单药治疗由退行性营养不良脊椎损伤引起的慢性下背痛具有很高的疗效。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
30
审稿时长
4 weeks
期刊介绍: ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.
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