A Study of Respiratory Syncytial Virus Outbreak at Postpartum Care Center in Busan, Korea

Abstract

Respiratory syncytial virus (RSV) is common cause of acute respiratory infection in infants and young children Group life in postpartum care centers is easily exposed to infectious diseases in neonates and puerperds immediately after giving birth, and the harm caused by exposure to them is much greater In particular, respiratory diseases are highly infectious and infections occur in a short period of time among them, RSV infections are very serious in children under 5 years of age, leading to death This paper studied an infection of RSV in outbreaks at postpartum care center in Busan In 4 postpartum care centers, a total of 877 people (390 neonates, 386 puerperds, 106 others) were exposed to RSV outbreak Of these, there were 73 RSV-positive patients;most of them had cough and runny nose and no fever We were collected from neonates and puerperds with acute respiratory tract a total of 146 samples (throat swabs) In 51 samples, RSV (43 cases), human rhinovirus (6 cases), human coronavirus NL63 (1 case), and human coronavirus 229E (1 case) were found to be positive and the rest were negative All 43 RSV positive samples were identified as RSV B Sequence analysis of the detected strains was performed to confirm the molecular genetic information of RSV Out of 43 RSV positive samples, 38 samples were successfully sequenced using the G gene, resulting in all of the same genotype BA9 This study provides a better understanding of RSV prevalence patterns and genetic characteristics It also contributes to the accumulation of epidemiological data and the development of public health and hygiene