Recurrence risk factors in elderly patients with stage II colorectal cancer

Abstract

Background: We investigated the risk factors for recurrence in high risk stage II colorectal cancer patients over 75 years old. Methods: This study included 79 patients who underwent primary colorectal surgery at Minami Kyousai Hospital from January 2015 to June 2019. The inclusion criteria were as follows: (1) age over 75 years old, (2) histologically confirmed stage II colorectal adenocarcinoma after curative surgery, and (3) no other active malignancy. A Cox proportional hazards model was used to identify the risk factors for recurrence. Results: The recurrence free survival rates at 1, 2, and 3 years after surgery were 92.6%, 78.8%, and 61.9%. The risk factors for recurrence were tumor location and lymph-node dissection. Conclusion: This study revealed that left-sided colorectal cancer and under D2 dissection are risk factors for recurrence of stage II colorectal cancer in the elderly. Patients with these risk factors should be considered for adjuvant chemotherapy.