A prospective observational study to assess the efficacy of “SICK” score in pediatrics

Shalini Thangaraj, Ilamaran Veerappan, SVenkatesh Karthik
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Abstract

Background: There is a need for pediatric scoring systems to monitor the progress in clinical outcomes, which are noninvasive, reliable, and easily measurable. Subjects and Methods: This prospective observational study evaluated the utility of a prevalidated “SICK” score for the purpose of assessing the score's efficacy in hospitalized children of age 1 month to 12 years. Results: Of the 531 cases, 145 (27.3%) were admitted to the pediatric intensive care unit (PICU) and 386 (72.7%) were admitted to the pediatric ward. The probability of PICU admission was 11.42 (95% confidence interval [CI] 6.3–20.7) when the “SICK” score was ≥2. Children with a score ≥2 had a significantly longer duration of stay (mean difference = 45.58 h, 95% CI [30.65–60.51], P = 0.001). The score performed with an area under curve of 0.691 for a cut off score. The positive predictive value of the score is 73.53% (95% CI 62.66–82.13) and the negative predictive value is 79.48% (95% CI 77.45–81.37). Conclusions: The score performed reasonably well in our center for a profile of moderately sick children and can be recommended to be used as an effective triaging tool in a similar setting.
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一项评估儿科“SICK”评分效果的前瞻性观察研究
背景:需要一种无创、可靠且易于测量的儿科评分系统来监测临床结果的进展。受试者和方法:这项前瞻性观察性研究评估了预先验证的“SICK”评分的效用,以评估该评分在1个月至12岁住院儿童中的疗效。结果:在531例病例中,145例(27.3%)入住儿科重症监护室(PICU),386例(72.7%)入住儿科病房。当“SICK”评分≥2时,PICU入院的概率为11.42(95%置信区间[CI]6.3–20.7)。得分≥2的儿童的住院时间明显更长(平均差异=45.58小时,95%置信区间[30.65-60.51],P=0.001)。该得分的截止得分曲线下面积为0.691。该评分的阳性预测值为73.53%(95%CI 62.66–82.13),阴性预测值为79.48%(95%CI 77.45–81.37)。
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审稿时长
8 weeks
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