Clinical effects of different surgical treatment on endometrial cancer in elderly patients

Abstract

Objective To investigate the surgical methods and their effects on endometrial cancer in the elderly, in order to provide the reference for clinical treatment plans. Methods From January to December 2018, 90 elderly patients with endometrial cancer in our hospital were treated with the conventional radical hysterectomy(the control group, n=45)and the extensive hysterectomy with pelvic autonomic nerve(the observation group, n=45). The operation and postoperative complications of the two groups were observed and analyzed. Results There was no significant difference in the operation time and intraoperative blood loss between the two groups(t=1.305 and 0.240, P=0.097 and 0.405), but the patients had the postoperative extubation time, exhaust time and defecation time in the observation group were significantly shorter than in the control group(9.5±1.6 d vs.13.8±1.7 d, 35.6±4.7 h vs.45.1±4.2 h, 70.3±7.6 h vs.84.5±6.6 h, t=12.356, 10.110, 9.463 and 29.160, respectively, all P=0.000). The total incidence of postoperative complications was lower in the observation group than in the control group(11.11% or 5/45 vs.35.56% or 16/45, χ2=7.516, P=0.006). Conclusions Compared with the traditional radical hysterectomy, extensive hysterectomy with systematic preservation of pelvic nerve for the treatment of endometrial cancer can significantly reduce surgical trauma, protect pelvic function and promote postoperative recovery, and it has a positive effect on long-term quality of life in the elderly. Key words: Endometrial neoplasms; Hysterectomy; Autonomic nervous system