Transcatheter aortic valve replacement in Bicuspid Aortic Valve Disease: An Insight

Varshil Mehta, Nikhil Nalluri, Varun Kumar, Nileshkumar J Patel, V. Atti, Arvin Narula, Mauricio G. Cohen
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Abstract

As per the current scenario, role of Transcatheter aortic valve replacement (TAVI) is controversial in bicuspid aortic valve stenosis. All the randomized clinical trials comparing outcomes of TAVI with surgery till date, have excluded patients with bicuspid aortic valve. Some of the observational studies have reported outcomes of TAVI in bicuspid aortic valve stenosis patients who are not surgical candidate. The recent advances in TAVI and its expansion into intermediate groups, which includes younger age groups sparks a debate on the efficacy and safety of TAVI in Bicsuspid aortic valve (BAV). The purpose of the present article is to review the available literature regarding the feasibility, safety and outcomes of TAVI in bicuspid aortic valve stenosis.
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经导管主动脉瓣置换术治疗双尖瓣主动脉瓣疾病
根据目前的情况,经导管主动脉瓣置换术(TAVI)在双尖瓣主动脉瓣狭窄中的作用存在争议。迄今为止,所有比较TAVI与手术结果的随机临床试验都排除了患有双尖瓣主动脉瓣的患者。一些观察性研究报道了TAVI在非手术候选人的二尖瓣主动脉瓣狭窄患者中的结果。TAVI的最新进展及其向包括年轻年龄组在内的中间组的扩展引发了关于TAVI在双主动脉瓣(BAV)中的有效性和安全性的争论。本文的目的是回顾关于TAVI治疗双尖瓣主动脉瓣狭窄的可行性、安全性和结果的现有文献。
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