Current management strategies of urachal anomalies in pediatric patients: A scoping review.

IF 1.1 Frontiers in urology Pub Date : 2023-03-17 eCollection Date: 2023-01-01 DOI:10.3389/fruro.2023.1159439
Yasmine S Ghattas, David G Gelikman, Kristen R Ibanez, Pamela Ellsworth, Abhishek Seth
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Abstract

Introduction: Management of urachal anomalies in pediatric patients has historically lacked a clear consensus between conservative and surgical management. We aimed to review and summarize the literature on the diagnosis, symptoms, and evolution in the management of urachal anomalies in pediatric patients.

Methods: We performed a scoping literature review of PubMed/Medline and WebOfScience from January 2000 to February 2022.

Results: 32 publications were selected for inclusion in this analysis. 1,438 unique studies were identified with 32 studies meeting inclusion criteria. 15/32 studies discussed both conservative and surgical management, 14/32 studies discussed only surgical management outcomes, and 3/32 studies discussed diagnostic methods. The studies discussing conservative management supported the treatment of urachal anomalies with an initial conservative approach, which includes watchful waiting, repeated ultrasounds, lesion measurement, and antibiotic use. 5/32 of the included studies identified patients that were converted from conservative to surgical management with conversion rates ranging from 12.5% to 43.5% per study. 14/20 converted patients were identified to have a urachal cyst and 13/20 had a persistent infection.

Conclusions: Strong evidence exists that supports initial conservative management over surgical management of pediatric urachal anomalies. However, predictive factors for determining which patients will require surgical management remain elusive. Treatment algorithms can potentially be developed once carefully developed prospective studies delineate statistically significant patient factors which necessitate surgical management over observation.

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儿科患者尿管异常的当前管理策略:范围综述
引言儿科患者脐尿管异常的治疗历来缺乏保守治疗和外科治疗之间的明确共识。我们旨在回顾和总结有关儿科患者脐尿管异常的诊断、症状和治疗进展的文献。方法2000年1月至2022年2月,我们对PubMed/Medline和WebOfScience进行了范围界定文献综述。结果选择了32篇出版物纳入本分析。确定了1438项独特的研究,其中32项研究符合纳入标准。15/32项研究同时讨论了保守治疗和手术治疗,14/32项研究仅讨论了手术治疗结果,3/32项研究讨论了诊断方法。讨论保守治疗的研究支持了脐尿管异常的初步保守治疗方法,包括密切等待、重复超声波、病变测量和抗生素使用。5/32的纳入研究确定了从保守治疗转为手术治疗的患者,每次研究的转化率在12.5%至43.5%之间。14/20的转化患者被发现有脐尿管囊肿,13/20的患者有持续感染。结论有强有力的证据支持对儿童脐尿管异常进行初步保守治疗而非手术治疗。然而,确定哪些患者需要手术治疗的预测因素仍然难以捉摸。一旦精心开发的前瞻性研究描绘出具有统计学意义的患者因素,就有可能开发出治疗算法,这些因素需要手术管理而非观察。
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