Applications of nanotechnology in the treatment of pulmonary diseases

Rahit Kumar Dey, Bachaspati Jana, Debabrata Ghosh Dastidar
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Abstract

Air pollution is a major concern for the global health crisis due to pulmonary diseases, which include asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, pneumonia, lung infections, and lung cancer. Early diagnosis and novel drug delivery systems are the keys to their successful management. Asthma and COPD can be managed more effectively when treated with nanoformulations through the pulmonary route. In lung infections and cancer, targeted drug delivery is crucial in improving therapeutic effectiveness while minimizing systemic side effects. Cystic fibrosis can be treated with gene therapy. It serves as a prime example of the utilization of nanotechnology for developing nonviral vectors. This review provides an overview of the causes of different pulmonary diseases and examines the advancements in nanoscience and nanotechnology for their treatment.
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纳米技术在肺部疾病治疗中的应用
由于肺部疾病,空气污染是全球健康危机的一个主要问题,包括哮喘、慢性阻塞性肺病(COPD)、肺纤维化、肺炎、肺部感染和癌症。早期诊断和新型药物输送系统是其成功管理的关键。通过肺部途径使用纳米制剂治疗哮喘和慢性阻塞性肺病可以更有效地进行治疗。在肺部感染和癌症中,靶向药物递送对于提高治疗效果同时最大限度地减少全身副作用至关重要。囊性纤维化可以用基因治疗。它是利用纳米技术开发非病毒载体的一个典型例子。这篇综述概述了不同肺部疾病的病因,并考察了纳米科学和纳米技术在治疗方面的进展。
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