Challenge of coronavirus disease 2019-related myocarditis diagnosis in patients with negative real-time polymerase chain reaction test: A case series

Abstract

Severe acute respiratory syndrome coronavirus 2 (CoV-2), the cause of CoV disease 2019 (COVID-19), can lead to multi-organ injury including cardiac involvement. Acute myocarditis is one of the serious and fatal complications of COVID-19. In this report, we introduce two cases with acute myocarditis and negative real-time polymerase chain reaction test, presented during the COVID-19 pandemic and discuss the challenge of their diagnosis and management.