{"title":"ACE inhibitors and ARBs","authors":"Tyler Sturdivant, Katrina Allen-Thomas","doi":"10.1097/01.nme.0000904948.57118.72","DOIUrl":null,"url":null,"abstract":"The renin-angiotensin-aldosterone system (RAAS) helps maintain haemodynamic stability by regulating blood pressure (BP), water, and electrolyte balance. Inappropriate or abnormal activation of the system can lead to excessive vasoconstriction, abnormal muscular hypertrophy, and fibrosis. This is associated with many cardiovascular disorders including hypertension, chronic heart failure (CHF), myocardial infarction (MI), and stroke, and with renal disorders such as diabetic nephropathy. The RAAS and pharmacological targets for current therapies are shown in figure 1 (page 4).","PeriodicalId":35379,"journal":{"name":"Nursing Made Incredibly Easy","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nursing Made Incredibly Easy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/01.nme.0000904948.57118.72","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 1
Abstract
The renin-angiotensin-aldosterone system (RAAS) helps maintain haemodynamic stability by regulating blood pressure (BP), water, and electrolyte balance. Inappropriate or abnormal activation of the system can lead to excessive vasoconstriction, abnormal muscular hypertrophy, and fibrosis. This is associated with many cardiovascular disorders including hypertension, chronic heart failure (CHF), myocardial infarction (MI), and stroke, and with renal disorders such as diabetic nephropathy. The RAAS and pharmacological targets for current therapies are shown in figure 1 (page 4).
期刊介绍：
Nursing made Incredibly Easy! is based on Lippincott Williams & Wilkins"s popular and successful Incredibly Easy! book series for nurses. The emphasis of Nursing made Incredibly Easy! is on breaking down challenging clinical concepts-the ones that are often difficult or confusing to grasp-and presenting them in a refreshingly original, easily understood, and engaging format. The tone is lighthearted, but never simplistic, to make learning fun and effective. Clinical artwork mixed with humorous line drawings illustrate and reinforce key points. Articles are contributed by experienced clinicians, ensuring that content is based on sound clinical principles and hands-on expertise.
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