Epidemiological profile and temporal trend of exogenous intoxications in children and adolescents

IF 1.4 Q3 PEDIATRICS Revista Paulista De Pediatria Pub Date : 2022-05-27 DOI:10.1590/1984-0462/2022/40/2021004IN
M. Melo, G. Santana, Matheus Henrique Almeida Rocha, R. Lima, Talles Alberto Bispo da Silva, C. D. F. Souza, Amanda Karine Barros Ferreira Rodrigues
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引用次数: 1

Abstract

Abstract Objective: To describe the epidemiological profile and to analyze the trend in the incidence rate of exogenous poisoning concerning children and adolescents (0–19 years old) in the city of Arapiraca, Alagoas, Brazil, in the period from 2007 to 2015. Methods: Observational study with data extracted from the Notifiable Diseases Information System. The variables sex, age group, toxic agent, and circumstance were analyzed using descriptive statistics. For temporal analysis, cut-off rates of incidence/10,000 inhabitants were calculated and the inflection point regression model was used for analysis. Results: There were 5,539 cases of exogenous intoxication in individuals aged 0–19 years in the city, of which 53.1% (n=2,944) occurred in girls and 61.5% (n=3,405) in children aged 0–9 years. Medicines consisted in the main agent responsible for intoxications (28.5%; n=1,580), mainly by accidental use (18.2%; n=1,010). There was a significant increase in the events during the study period (Average Annual Percent Change: 12.7; 95%CI 1.1–25.6; p<0.001), with rates increasing from 56.52/10,000 inhabitants in 2007 to 56.64/10,000 inhabitants in 2015. The incidence of cases in girls increased from 57.34/10,000 inhabitants in 2007 to 62.27/10,000 inhabitants in 2015. In boys, the incidence of cases was stationary: 55.69/10,000 inhabitants to 50.9 /10,000 inhabitants in the same period. Conclusions: The study showed a higher frequency of cases in girls aged 0 to 4 years and an increasing trend in the incidence rate during the study period. Implementation of actions and strategies, with emphasis on health education, is needed in order to prevent cases of exogenous intoxication.
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儿童和青少年外源性中毒的流行病学概况和时间趋势
摘要目的:描述2007-2015年巴西阿拉戈斯阿拉皮拉卡市儿童和青少年(0–19岁)外源性中毒的流行病学特征,并分析其发病率趋势。方法:采用从法定疾病信息系统中提取的数据进行观察研究。使用描述性统计分析变量性别、年龄组、毒性因素和环境。对于时间分析,计算了每10000名居民的发病率临界值,并使用拐点回归模型进行分析。结果:该市0~19岁个体发生外源性中毒5539例,其中53.1%(n=2944)发生在女孩身上,61.5%(n=3405)发生在0~9岁儿童身上。药物是导致中毒的主要药物(28.5%;n=1580),主要是意外使用(18.2%;n=1010)。在研究期间,事件显著增加(平均年百分比变化:12.7;95%置信区间1.1-25.6;p<0.001),发病率从2007年的56.52/000居民增加到2015年的56.64/1000居民。女孩的发病率从2007年的57.34/000居民增加到2015年的62.27/1000居民。在男孩中,病例发生率是稳定的:同期为55.69/10000居民至50.9/1000居民。结论:研究表明,0至4岁女孩的病例发生率较高,在研究期间发病率呈上升趋势。需要实施行动和战略,重点是健康教育,以预防外源性中毒。
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来源期刊
Revista Paulista De Pediatria
Revista Paulista De Pediatria Medicine-Pediatrics, Perinatology and Child Health
CiteScore
2.30
自引率
0.00%
发文量
100
审稿时长
11 weeks
期刊介绍: The Revista Paulista de Pediatria publishes original contributions, case reports and review of clinical research with methodological approach in the areas of health and disease of neonates, infants, children and adolescents. The objective is to disseminate research with methodological quality on issues that comprise the health of children and adolescents. All articles are freely available online, via SciELO. Its abbreviated title is Rev. Paul. Pediatr., which should be used in bibliographies, footnotes and bibliographical references and strips.
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