The predictive role of fully revascularized coronary artery disease in patients undergoing transaortic valve implantation

R. Pencheva, J. Shabani, D. Trendafilova, J. Jorgova, H. Angelov, P. Simeonov, I. Dimitrova
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Abstract

In the modern days and the era of the rapid development of medical technology, the introduction of innovative invasive methods of treatment is gradually displacing traditional conventional surgery. In 2002 was performed the fi rst transcatheter implantation of an aortic valve. Over the next twenty years, with the advancement of technology and the accumulation of experience in clinical centers, transcatheter aortic valve implantation has become the standard in adult and high-risk patients with high-grade Ao stenosis. In a large percentage of cases enrolled under the transcatheter aortic valve protocol a concomitant ischemic heart disease is detected or known. Globally, there is no signifi cant difference in overall mortality on the thirtieth day after TAVI in patients with ischemic heart disease. However, the overall mortality was signifi cantly higher in one – year follow - up of patients after transcatheter aortic valve implantation with underlying coronary pathology. We conducted a study comparing the number of late and early adverse events in patients with concomitant fully revascularized ischemic heart disease and those with insignifi cant coronary atherosclerosis. Based on the data collected, analyzed and summarized in our clinical center, fully revascularized ischemic heart disease does not increase the percentage of major adverse events after transcatheter aortic valve implantation. It can be considered when assessing the risk of transcatheter aortic implantation, as part of the individual approach for each case.
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完全血运重建的冠状动脉疾病在经主动脉瓣植入患者中的预测作用
在当今医疗技术飞速发展的时代,创新的侵入性治疗方法的引入正逐渐取代传统的常规手术。2002年进行了第一例经导管主动脉瓣植入术。在接下来的二十年里,随着技术的进步和临床中心经验的积累,经导管主动脉瓣植入术已成为成人和高危高级别Ao狭窄患者的标准。在经导管主动脉瓣方案下登记的大部分病例中,检测到或已知伴有缺血性心脏病。在全球范围内,缺血性心脏病患者TAVI后第30天的总死亡率无显著差异。然而,经导管主动脉瓣置入术后有潜在冠状动脉病变的患者,在一年的随访中,总死亡率明显更高。我们进行了一项研究,比较了合并完全血运重建的缺血性心脏病患者和不明显冠状动脉粥样硬化患者的晚期和早期不良事件的数量。根据我们临床中心收集、分析和总结的数据,经导管主动脉瓣植入术后,完全血运重建的缺血性心脏病不会增加主要不良事件的百分比。在评估经导管主动脉植入术的风险时,可以考虑将其作为每个病例的个别方法的一部分。
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CiteScore
0.10
自引率
0.00%
发文量
40
审稿时长
12 weeks
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