Assessment of Monte Carlo Geant4 capabilities in prediction of photon beam dose distribution in a heterogeneous medium

Q3 Medicine Physics in Medicine Pub Date : 2018-06-01 DOI:10.1016/j.phmed.2017.08.001
Jaafar EL Bakkali , Abderrahim Doudouh , Hamid Mansouri
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引用次数: 3

Abstract

The aim of this study is the assessment of the Geant4 capabilities in accurately modeling of dose distribution in a heterogeneous water phantom. In this purpose, a Geant4 user code has been designed and developed to enable an accurate modeling of cross beam profiles in a heterogeneous water phantom deposited by a 12 MV photon beam emitted by a Saturne 43 Linac head and configuring a 10 × 10 cm2 radiation field. The calculated cross beam profiles at two distinct depths (22 cm and 25 cm), were compared to the ones obtained with MCNPX code. Our findings show that the shapes of dosimetric curves at two distinct depths calculated with Geant4 code and the ones obtained by MCNPX code are in a very good agreement. However, the Geant4 code seems painfully slow when calculating those dosimetric curves and its associated statistical uncertainties don't seem to reach 1% after two weeks of calculations. To deal with this issue, we suggest that a new variance reduction technique specially addressed for dose calculation in a heterogeneous medium must be developed by the Geant4 collaboration, in order to decrease the required computing time and to improve the statistical of calculations.

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评价蒙特卡罗Geant4在非均匀介质中预测光子束剂量分布的能力
本研究的目的是评估Geant4在非均匀水影中准确建模剂量分布的能力。为此,设计并开发了一个Geant4用户代码,以实现由Saturne 43直线加速器头发射的12 MV光子束沉积的非均质水影中的交叉光束剖面的精确建模,并配置了10 × 10 cm2的辐射场。计算的两个不同深度(22 cm和25 cm)的横梁轮廓与MCNPX代码的计算结果进行了比较。结果表明,用Geant4程序计算的两个不同深度的剂量学曲线形状与MCNPX程序计算的曲线形状吻合得很好。然而,在计算这些剂量曲线时,Geant4代码似乎慢得令人痛苦,其相关的统计不确定性在计算两周后似乎没有达到1%。为了解决这一问题,我们建议必须由Geant4合作开发一种专门针对非均匀介质中剂量计算的新的方差减少技术,以减少所需的计算时间并提高计算的统计性。
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来源期刊
Physics in Medicine
Physics in Medicine Physics and Astronomy-Instrumentation
CiteScore
2.60
自引率
0.00%
发文量
9
审稿时长
12 weeks
期刊介绍: The scope of Physics in Medicine consists of the application of theoretical and practical physics to medicine, physiology and biology. Topics covered are: Physics of Imaging Ultrasonic imaging, Optical imaging, X-ray imaging, Fluorescence Physics of Electromagnetics Neural Engineering, Signal analysis in Medicine, Electromagnetics and the nerve system, Quantum Electronics Physics of Therapy Ultrasonic therapy, Vibrational medicine, Laser Physics Physics of Materials and Mechanics Physics of impact and injuries, Physics of proteins, Metamaterials, Nanoscience and Nanotechnology, Biomedical Materials, Physics of vascular and cerebrovascular diseases, Micromechanics and Micro engineering, Microfluidics in medicine, Mechanics of the human body, Rotary molecular motors, Biological physics, Physics of bio fabrication and regenerative medicine Physics of Instrumentation Engineering of instruments, Physical effects of the application of instruments, Measurement Science and Technology, Physics of micro-labs and bioanalytical sensor devices, Optical instrumentation, Ultrasound instruments Physics of Hearing and Seeing Acoustics and hearing, Physics of hearing aids, Optics and vision, Physics of vision aids Physics of Space Medicine Space physiology, Space medicine related Physics.
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