Antioxidants and Antityrosinase Activity of Ethanolic Basil Leaves Extract (Ocimum americanum L.) and Eygenol

Dio Damara Handoyo, E. Girsang, A. N. Nasution, N. Lister
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引用次数: 2

Abstract

Harm effect from UV light, both UV-A and UV-B is contributing as a disease trigger and has an impact on human health. To investigate the bioactive compound, antioxidant, and the potential of basil leaves as antiaging sources particularly as the tyrosinase inhibitor. This study used phytochemical screening for the bioactive compound, DPPH scavenging activity for antioxidant assay, and tyrosinase inhibition activity for the antiaging property. The phytochemical screening shows that the basil leaves extract has flavonoid, saponin, phenol, steroid, and alkaloid. The basil leaves extract has lower antioxidant activity (20.55 ± 0.04 μg/mL) compared with eugenol (2.44 ± 0.26 μg/mL) through DPPH scavenging activity. The basil leaves extract (35.59 ± 0.83 μg/mL) has lower antiaging activity particularly as antityrosinase activity compared with eugenol (10.87 ± 0.41 μg/mL). Our findings suggest that basil leaves can be used as an antioxidant and antiaging source, particularly as a tyrosinase inhibitor.
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罗勒叶乙醇提取物和Eygenol的抗氧化活性及抗酪氨酸酶活性
紫外线的危害作用,无论是紫外线a还是紫外线b,都是疾病的诱因,对人体健康有影响。研究罗勒叶的生物活性化合物、抗氧化剂和作为抗衰老来源的潜力,特别是作为酪氨酸酶抑制剂。本研究采用植物化学筛选方法对其生物活性化合物进行筛选,对DPPH清除活性进行抗氧化试验,对酪氨酸酶抑制活性进行抗衰老试验。植物化学筛选表明,罗勒叶提取物含有黄酮类化合物、皂苷类化合物、酚类化合物、甾体化合物和生物碱。罗勒叶提取物对DPPH的清除活性(20.55±0.04 μg/mL)低于丁香酚(2.44±0.26 μg/mL)。罗勒叶提取物(35.59±0.83 μg/mL)的抗衰老活性低于丁香酚(10.87±0.41 μg/mL)的抗酪氨酸酶活性。我们的研究结果表明罗勒叶可以作为抗氧化剂和抗衰老的来源,特别是作为酪氨酸酶抑制剂。
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
10
审稿时长
15 weeks
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