Bioactive Lignans from Flaxseed: Biological Properties and Patented Recovery Technologies

Nutraceuticals Pub Date : 2023-01-10 DOI:10.3390/nutraceuticals3010005

P. Sangiorgio, S. Errico, A. Verardi, S. Moliterni, G. Tamasi, C. Rossi, R. Balducchi

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引用次数: 3

Abstract

Flaxseed lignans frequently feature in the literature. However, much remains to be discovered about the mechanisms underlying their functional and therapeutic properties. Furthermore, it is necessary to identify systems for lignan production and detoxification that are sustainable, cost-effective, easy to use, and scale up. These systems can address the needs of the nutraceutical, cosmetic, and pharmaceutical sectors and lead to competitive commercial products. This review analyzes the biological effects of lignans as anticancer, antioxidants, and modulators of estrogen activity. It also focuses on the most recent articles on lignan extraction methods that are sustainable and suitable as products for human consumption. Furthermore, the most up-to-date and relevant patents for lignan recovery are examined. The search and selection methodology for articles and patents was conducted using the most popular bibliographic and patent databases (e.g., Scopus, Pubmed, Espacenet). To the best of our knowledge, this is the first overview that details the patented technologies developed in the flaxseed lignans area in the last 10 years.

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亚麻籽中的生物活性木脂素:生物学特性和专利回收技术

亚麻木脂素经常出现在文献中。然而，关于其功能和治疗特性的机制还有很多有待发现。此外，有必要确定可持续、成本效益高、易于使用和扩大规模的木脂素生产和解毒系统。这些系统可以满足营养品、化妆品和制药行业的需求，并产生具有竞争力的商业产品。本文综述木脂素作为抗癌、抗氧化剂和雌激素活性调节剂的生物学作用。它还关注了关于木脂素提取方法的最新文章，这些方法是可持续的，适合作为人类消费的产品。此外，还审查了木脂素回收的最新相关专利。文章和专利的搜索和选择方法是使用最流行的书目和专利数据库（例如Scopus、Pubmed、Espacnet）进行的。据我们所知，这是过去10年来首次详细介绍亚麻木脂素领域开发的专利技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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