Implications of Disrupted Circadian Rhythms on Pain.

Journal of psychiatry and brain science Pub Date : 2021-01-01 Epub Date: 2021-08-06 DOI:10.20900/jpbs.20210014
Jacob R Bumgarner, Randy J Nelson
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Abstract

Pain is regulated by circadian rhythms. Daily fluctuations in pain thresholds are observed in health and disease. Disruptions to the circadian and pain systems may initiate a detrimental feedback loop between the two systems. The relationship between the pain and circadian systems is briefly reviewed to highlight a perspective on the need to consider disrupted circadian rhythms in the treatment of pain.

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昼夜节律紊乱对疼痛的影响
疼痛是由昼夜节律调节的。在健康和疾病中观察到疼痛阈值的每日波动。昼夜节律和疼痛系统的破坏可能在这两个系统之间引发有害的反馈回路。简要回顾了疼痛和昼夜节律系统之间的关系,以强调在治疗疼痛时需要考虑昼夜节律紊乱。
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