Pesticides and public health in Brazil

Francisco J.R. Paumgartten
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引用次数: 30

Abstract

Brazil is one of the world's top-four agricultural pesticide–consuming countries. The extensive use of pesticides raises concerns about the consequences for the human health. This review appraised the evidence provided by epidemiological studies on the adverse health effects of pesticides conducted in Brazil within the past 2–4 years. Available data come from ecological, cross-sectional, and case–control studies which are relatively easy, quick, and inexpensive to conduct but of limited usefulness for inferring causation and to identify hazards in pesticide risk assessment. Inaccurate exposure assessment is another weakness common to these studies. No longitudinal cohort investigation of pesticide adverse health effects and no analytical data–based biomonitoring study were found in the literature. In conclusion, studies conducted in Brazil failed to generate data relevant for risk assessment and management of pesticides. Large prospective cohorts studies and good analytical data on exposures are needed to bridge this public health research gap.

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巴西的农药与公共卫生
巴西是世界四大农业农药消费国之一。农药的广泛使用引起了人们对其对人类健康的影响的关注。本综述评价了过去2-4年内在巴西开展的关于农药对健康不利影响的流行病学研究所提供的证据。现有数据来自生态、横断面和病例对照研究,这些研究相对容易、快速和廉价,但在推断因果关系和确定农药风险评估中的危害方面用处有限。不准确的暴露评估是这些研究的另一个共同弱点。文献中未发现农药不良健康影响的纵向队列调查,也未发现基于分析数据的生物监测研究。总之,在巴西进行的研究未能产生与农药风险评估和管理有关的数据。需要大规模前瞻性队列研究和良好的暴露分析数据来弥合这一公共卫生研究差距。
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来源期刊
Current opinion in toxicology
Current opinion in toxicology Toxicology, Biochemistry
CiteScore
8.50
自引率
0.00%
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0
审稿时长
64 days
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