Mentzer and RDW Index in the Establishment of Iron Deficiency Anemia Diagnosis in the First Trimester of Pregnant Woman

Abstract

Objective: To determine the sensitivity and specificity of the Mentzer and RDW index to assist in the diagnosis of iron deficiency anemia in first trimester pregnant women at RSIA Asih. Methods: This research was conducted by a cross-sectional method using the medical records of 100 samples of first trimester pregnant women with iron deficiency anemia by consecutive sampling and 100 samples of controls, which is also first trimester pregnant women with anemia. The data is then analyzed using Kolmogorov-Smirnov test and the independent-T test. Result: This study showed a significant relationship between the Mentzer index and the RDW index in iron deficiency anemia patients and control with p value = 0.000. Calculated by the ROC curve, the cut-off of Mentzer and RDW indices were 18.33 (sensitivity 37%, specificity 36%) and 249.2 (sensitivity 36%, spesificity 36%). Calculated by chi-square, the sensitivity and specificity values of the Mentzer index were 69% and 22% (literacy cut-off = 13), while the sensitivity and specificity values of the RDW index were 63% and 34% (literacy cut-off = 220). Conclusion: Mentzer index and RDW index cannot be proposed as the main parameter to help the establisment of iron deficiency anemia diagnosis in first trimester pregnant women.