25 Years of Molecular Psychology: The best is yet to come

T. Canli
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Abstract

This editorial defines the scope of the field of Molecular Psychology, which refers to the study of behavior and its underlying neural systems using the toolset of molecular biology, particularly molecular genetics and epigenetics. It is related to other well-established fields that use molecular tools in animal model organisms (Behavioral Neuroscience; Neuroethology) or that focus on molecular mechanisms of human mental health and disease (Molecular Psychiatry; Health Psychology), but extends beyond these fields by its inclusion of broad domains of human behavior; the precise molecular mechanisms by which environmental exposure and experiences modify gene expression; and the ethical, legal, and social implications (ELSI) of these discoveries. Considering the first 25 years of studies that included candidate gene and genome-wide association studies, I suggest a roadmap for the next decade of work. On the launch of F1000 Molecular Psychology: Brain, Behavior & Society, I hope this publication platform will become instrumental in growing this field by promoting a spirit of support and community among its practitioners, embracing transparency and rigor, and publishing novel ideas and studies ranging from pilot and proof-of-concept first steps to gold-standard definitive milestones.
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分子心理学25年:最好的还在后头
这篇社论定义了分子心理学领域的范围,它指的是使用分子生物学,特别是分子遗传学和表观遗传学的工具集来研究行为及其潜在的神经系统。它与其他在动物模式生物中使用分子工具的成熟领域有关(行为神经科学;神经行为学)或专注于人类心理健康和疾病的分子机制(分子精神病学;健康心理学),但它超越了这些领域,包括人类行为的广泛领域;环境暴露和经历改变基因表达的精确分子机制;以及这些发现的伦理、法律和社会影响(ELSI)。考虑到前25年的研究,包括候选基因和全基因组关联研究,我建议未来十年的工作路线图。在F1000分子心理学:大脑,行为与社会发布之际,我希望这个出版平台能够通过在从业者中促进支持和社区精神,拥抱透明度和严谨性,并发布新颖的想法和研究,从试点和概念验证的第一步到黄金标准的最终里程碑,在这一领域的发展中发挥重要作用。
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