Comparative Effects of Three Kinds of Bariatric Surgery: A Randomized Case-Control Study in Obese Patients.

IF 2.8 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM Diabetes Therapy Pub Date : 2020-01-01 Epub Date: 2019-12-03 DOI:10.1007/s13300-019-00719-7
Dan Luo, Qingling Yang, Li Zhou, Haibo Wang, Feng Li, Hailong Ge, He Huang, Jian Liu, Yanjun Liu
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引用次数: 4

Abstract

Introduction: Laparoscopic bariatric surgery is necessary for obese patients who cannot control body weight through daily diet and exercise, or other non-surgical ways. Three kinds of laparoscopic bariatric surgery, namely Roux-en-Y gastric bypass, sleeve gastrectomy, and sleeve gastrectomy with jejunal bypass, are available for weight loss in clinical practice, but their comparative effects are unclear. In this study, these were compared to illustrate their clinical effects.

Methods: A case-control study was conducted on 175 participants who fulfilled the inclusion criteria of laparoscopic bariatric surgery, while the controls were the same subjects before and after surgery, as well as with different surgeries specifically. Standardized weight loss measures were compared using analysis of covariance, with months from surgery as the covariant, including percentage total weight loss and excess body mass index (BMI) loss.

Results: A total of 175 patients were enrolled in this study (age 38 ± 10 years; BMI 46 ± 5 kg/m2), with a mean postsurgery follow-up of 18 ± 6 months. No significant difference was included among the enlisted patients before bariatric surgery. However, after surgery according to personal health indexes of patients and professional assessment by doctors, patients specifically receiving one of Roux-en-Y gastric bypass, sleeve gastrectomy, and sleeve gastrectomy with jejunal bypass had no significant difference between weight loss and BMI, while the most important factors were dietary control and exercise after bariatric surgery.

Conclusion: This study suggests that bariatric surgery is only a prerequisite for weight loss, and the long-term dietary control and exercise can help patients achieve optimal weight loss.

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三种减肥手术效果的比较:肥胖患者的随机病例对照研究
对于不能通过日常饮食和运动或其他非手术方式控制体重的肥胖患者,腹腔镜减肥手术是必要的。临床上有Roux-en-Y胃旁路术、套筒胃切除术、套筒胃切除术联合空肠旁路术三种腹腔镜减肥手术,但其对比效果尚不清楚。在本研究中,我们比较了它们的临床效果。方法:对175例符合腹腔镜减肥手术纳入标准的患者进行病例对照研究,对照组为手术前后及不同手术方式的受试者。采用协方差分析比较标准化减肥措施,以手术后数月为协变量,包括总体重减轻百分比和超重体重指数(BMI)减轻百分比。结果:共入组175例患者(年龄38±10岁;BMI 46±5 kg/m2),术后平均随访18±6个月。在减肥手术前,入选患者之间没有显著差异。但术后根据患者个人健康指标及医生专业评估,分别接受Roux-en-Y胃旁路术、袖胃切除术、袖胃切除术合并空肠旁路术其中一种的患者,其体重减轻和BMI无显著差异,而减肥手术后饮食控制和运动是最重要的因素。结论:本研究提示减肥手术只是减肥的先决条件,长期的饮食控制和运动可以帮助患者达到最佳的减肥效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diabetes Therapy
Diabetes Therapy Medicine-Endocrinology, Diabetes and Metabolism
自引率
7.90%
发文量
130
期刊介绍: Diabetes Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all areas of diabetes. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Diabetes Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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