Palliative surgery for malignant gastrointestinal obstruction: A community hospital experience

Megumi Sano, Shin-ichi Asaka, M. Satake, J. Kinoshita, Masaki Matsumura, S. Takiguchi, Yoshitomo Ito, R. Imaizumi, S. Mitsuboshi, T. Matsumoto, T. Koike, S. Shiozawa, K. Yoshimatsu
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Abstract

Aim: To assess the efficacy of palliative surgery on malignant gastrointestinal obstruction (MGIO), we analyzed postoperative results in patients underwent palliative surgery for the purpose of symptom relief. Patients and methods: Seventeen patients with MGIO were enrolled who underwent palliative surgery to release stenotic symptoms. Post-operative course and prognosis were retrospectively analyzed. Results: The median time to take first diet was 4 days excluding three patients who were unable to eat. Complications more than grade II in Clavien Dindo classification were observed in 3 cases. Thirty-day postoperative mortality was 17.3%. The median survival time (MST) was 148 days. Eleven out of 17 patients could be initiated chemotherapy. Duration of possible oral diet and home stay was significantly longer in patients with chemotherapy than in those without chemotherapy (p = 0.0035, p = 0.0008 respectively). A significantly prolonged survival was also observed (p = 0.0002). Conclusion: Early oral intake was possible by palliative surgery for MGIO. In cases with chemotherapy, it was considered possible to maintain a relatively long-term survival and QOL even in the terminal status.
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恶性胃肠梗阻的姑息性手术:社区医院的经验
目的:为了评估姑息手术治疗恶性胃肠道梗阻(MGIO)的疗效,我们分析了为缓解症状而接受姑息手术的患者的术后结果。患者和方法:纳入17名MGIO患者,他们接受了缓解狭窄症状的姑息性手术。回顾性分析术后病程及预后。结果:除三名无法进食的患者外,首次进食的中位时间为4天。在Clavien-Dindo分类中观察到3例并发症超过II级。术后30天死亡率为17.3%,中位生存时间(MST)为148天。17名患者中有11名可以开始化疗。化疗患者可能的口服饮食和居家时间明显长于未化疗患者(分别为p=0.0035和p=0.0008)。还观察到生存期显著延长(p=0.0002)。结论:MGIO的姑息性手术可以早期口服。在化疗的情况下,即使在晚期,也可以保持相对长期的生存率和生活质量。
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来源期刊
Annals of Cancer Research and Therapy
Annals of Cancer Research and Therapy Medicine-Pharmacology (medical)
CiteScore
0.70
自引率
0.00%
发文量
18
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