Efficacy and safety of Mailuo Shutong granule combined with low molecular weight heparin in the prevention of postoperative deep venous thrombosis: a systematic review and Meta-analysis

Abstract

Background: to systematically evaluate the efficacy and safety of Mailuo Shutong granule combined with low molecular weight heparin in the prevention of postoperative deep venous thrombosis (DVT). Methods: PubMed, EMbase, Cochrane Library, China knowledge Network (CNKI), Wanfang Medical Database, Chinese Biomedical Literature Database (SinoMed) and VIP Database were searched by computer from the establishment of the database to July 3, 2020. Search and collect randomized controlled trials of Mailuo Shutong granule combined with low molecular weight heparin in the prevention of postoperative DVT. Cochrane risk bias assessment tool was used to evaluate the quality of the included study, and RevMan5.3 software was used for meta-analysis. Results: A total of 61 articles about prevention of DVT after operation with Mailuo Shutong postoperative DVT were comprehensively evaluated by the method of Meta-analysis, so as to provide a basis for clinical decision-making. We present the following article in accordance with the PRISMA reporting checklist (available at http://dx.doi. org/10.21037/lcm-20-31). should be selected for outcome indicators.