Adult gonococcal keratoconjunctivitis: early detection is key

Daniel Lai, K. Ong
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Abstract

We describe a case of a 52-year-old male presenting with severe mucopurulent conjunctivitis of the right eye. Corneal ulceration and associated anterior chamber activity was noted later in the course of the disease. Neisseria gonorrhoeae was positive on polymerase chain reaction (PCR) testing earlier than traditional microscopy and culture. He was successfully treated with ceftriaxone 500 mg intravenously and azithromycin 1 g orally as single doses in addition to ofloxacin ophthalmic solution 0.3% hourly to the right eye. This case highlights the need to consider the possibility of gonococcus in cases of suspected bacterial conjunctivitis, careful monitoring for corneal involvement and the importance of early detection with PCR.
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成人淋球菌性角结膜炎:早期发现是关键
我们描述了一个52岁的男性表现为严重的粘液化脓性结膜炎的右眼。角膜溃疡和相关的前房活动在病程的后期被注意到。淋病奈瑟菌聚合酶链反应(PCR)检测阳性早于传统镜检和培养。在右眼滴注氧氟沙星眼液0.3% /小时的基础上,静脉滴注头孢曲松500 mg,单次口服阿奇霉素1 g,治疗成功。本病例强调了在疑似细菌性结膜炎病例中考虑淋球菌的可能性,仔细监测角膜受累情况以及PCR早期检测的重要性。
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Asian Journal of Ophthalmology
Asian Journal of Ophthalmology Medicine-Ophthalmology
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期刊介绍: Asian Journal of OPHTHALMOLOGY is the official peer-reviewed journal of the South East Asia Glaucoma Interest Group (SEAGIG) and is indexed in EMBASE/Excerpta Medica. Asian Journal of OPHTHALMOLOGY is published quarterly (four [4] issues per year) by Scientific Communications International Limited. The journal is published on-line only and is distributed free of cost via the SEAGIG website.
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