Seyyedeh Azade Hoseini Nouri, Manijeh Tabrizi, M. Zarkesh, A. Talebi, M. Shahrokhi, A. Hassanzadeh Rad, Setila Dalili, E. Kazemnezhad leili
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引用次数: 0
Abstract
Background and Objectives: Over the past three decades, the prevalence of overweight and obesity in children and adolescents has increased up to 3 times. Obesity is a multi-systemic medical problem affecting all socioeconomic statuses and increases the risk of other severe comorbidities even in childhood. In 50% of cases, there is a persistence of obesity from childhood into adulthood. This narrative review aimed to define the etiology, risk factors, prevention, and management of obesity in children. Methods: This narrative review was conducted through a literature search on articles in English with the keywords of pediatric obesity, child, overweight, and bariatric surgery in PubMed, Scopus, ISI Web of Sciences, Cochrane, and EMBASE databases from 2001 to 2021 for 4 categories of etiology, risk factors, prevention, and management of obesity in children. Scientific articles, systematic reviews, meta-analyses, consensus, recommendations, and international and national guidelines published on pediatric obesity were considered. Results: In this narrative review, we first assessed relevant articles to define childhood obesity and mention its etiologies. We then discussed the probability of persistent obesity from childhood into adulthood and intergenerational and perinatal transmission risks. We also noticed syndromic obesity, evaluation of childhood obesity, and its complications along with medical/surgical interventions. Conclusions: Metabolic programming in particular periods of life, such as before and during pregnancy, infancy, and at the age of rebound adiposity (5.5 years old), is necessary to prevent childhood obesity. Lifestyle changes, diet modifications, promoting exclusive breastfeeding, and increased activity are the main principles of preventing and managing obesity. It is prudent to rule out syndromic and endocrinologic causes of obesity in suspicious patients along with their management.
背景和目的:在过去三十年中,儿童和青少年中超重和肥胖的患病率增加了三倍。肥胖是一个影响所有社会经济地位的多系统医学问题,甚至在儿童时期也会增加其他严重合并症的风险。在50%的病例中,肥胖症从儿童期持续到成年期。本综述旨在明确儿童肥胖的病因、危险因素、预防和管理。方法:对2001 - 2021年PubMed、Scopus、ISI Web of Sciences、Cochrane和EMBASE数据库中以儿童肥胖、儿童、超重和减肥手术为关键词的英文文章进行文献检索,检索儿童肥胖的病因、危险因素、预防和管理4类。科学文章、系统综述、荟萃分析、共识、建议以及发表的关于儿童肥胖的国际和国家指南被考虑在内。结果:在这篇叙述性综述中,我们首先评估了相关的文章来定义儿童肥胖并提及其病因。然后我们讨论了从儿童期到成年期持续肥胖的可能性以及代际和围产期传播风险。我们还注意到综合征性肥胖、儿童肥胖的评估及其并发症以及医疗/手术干预。结论:在生命的特定时期,如怀孕前和怀孕期间,婴儿期和反弹肥胖年龄(5.5岁),代谢规划是预防儿童肥胖的必要条件。改变生活方式、调整饮食、促进纯母乳喂养和增加活动是预防和管理肥胖的主要原则。谨慎的做法是排除可疑患者肥胖的综合征和内分泌原因,并对其进行管理。