In recent years, with the promotion of national fitness, running has become one of the most popular sports, especially marathon. At the same time, people's attention to running injuries is also increasing, especially in the knee and ankle joints. Joint cartilage, as a component of joints, can cause joint degeneration and a series of joint diseases once damaged. MRI, as a non-invasive examination, can reflect the early biochemical changes of cartilage before the appearance of morphological changes, and has important value for early diagnosis of cartilage lesions. Currently, quantitative MRI techniques for cartilage mainly include T1 ρ、 T2 mapping, T2 * mapping, etc. The author reviews the progress of MRI quantitative research on the changes in articular cartilage caused by running.