Isolation and structural identification of a novel fructan from Radix Codonopsis

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2020-01-01 DOI:10.1080/07328303.2020.1772278
Jiankuan Li , Yan Wang , Xia Zhang , Lingya Cao , Jiaojiao Ji , Qinghong Zheng , Jianping Gao
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引用次数: 8

Abstract

Fructans are generally divided into two different types: β-D-fructofuranosyl-(2→1)-linked inulin and β-D-fructofuranosyl-(2→6)-linked levan. Previously, Radix Codonopsis was found to be rich in inulin type of fructans with low molecular weight (<5000 Da). In this study, a novel macromolecular fructan with a molecular weight of 1.70 × 103 KD was isolated from Radix Codonopsis, and its homogeneity was shown to be a single peak by high performance gel permeation chromatography (HPGPC), and its structure was confirmed to contain a new type of linkage, α-D-fructofuranosyl-(2→3)-β-D-fructofuranosyl linkage, by 1D- and 2D-nuclear magnetic resonance (NMR).

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党参中一种新果聚糖的分离与结构鉴定
摘要果聚糖通常分为两种不同的类型:β-D-呋喃果糖基-(2→1) -连接菊粉和β-D-呋喃果糖基-(2→6) -链接levan。以前,人们发现党参富含菊粉型低分子量果聚糖(<5000 Da)。在本研究中,一种分子量为1.70的新型大分子果聚糖 × 从党参中分离得到103KD,高效凝胶渗透色谱(HPGPC)显示其均一性为单峰,并证实其结构含有一种新型的连接,α-D-呋喃果基-(2→3) -β-D-呋喃果糖基连接,通过1D-和2D核磁共振(NMR)。图形摘要
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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