Nilgirianthus ciliatus mediated environment friendly extracellular synthesis of AgNps to exact its potential against Dengue vector, Aedes aegypti and Staphylococcus aureus

Abstract

Aedes aegypti, the dengue vector, is a menace continuing since 1780; it is due to development of resistant to synthetic insecticides and Staphylococcus aureus, the common microbial pathogen agent of food poisoning, skin infections and respiratory infections have developed multidrug resistant, which forced us to focus on novel agent for which the dengue vector and bacterial pathogen have not practiced to develop resistant and which cannot detoxify it using its usual enzyme activity as it did earlier. Silver nanoparticles a challenging insecticidal agents for the toxic degrading enzymes of both the insect and microbe was the target of our present study to excavate the potential in killing immature of dengue vector and bacterial pathogen. Green protocolled nanoparticles were successfully synthesized using leaf extract of Nilgirianthus ciliatus which act as reducing as well as capping agents. The UVvis spectra observed at 441nm confirmed the presence of silver nanoparticles. XRD and FT-IR confirmed the crystalline nature and organic capping around the silver nanoparticles respectively. SEM and DLS showed the average size at 117 nm and the particle dispersion was at -17.2mV zeta potential.