Outcome of Colorectal cancer in Geriatric Patient

A. Chandio, A. Rai, Mehak Chandio, Asirvatham Rhody, Katherine Brown
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Abstract

Background: Older surgical patients remain at increased risk of adverse postoperative outcome when undergoing both elective and emergency surgery. The needs of the older surgical patient are often substantially different from those of younger patients. As a surgeons we have dilemmas in appropriately treating elderly patients. Specifically, those with cancer have been shown to receive inappropriate care, being either undertreated or overtreated based on their chronological age rather than their degree of frailty. Aim:To evaluate outcome of patients diagnosed with colorectal cancer in patients aged 80 years and over. Methods:Retrospective study of all patients 80 years and above managed with colorectal cancer at the Luton and Dunstable University Hospital UK from January 2015 through December 2019 Results: In the study period 278 patients were diagnosed with colorectal cancer, Male 143 Female 135 ratio 1:1.05. Age range from 80 to 101years. 54.31% patients underwent surgical intervention. 15.10% had complications after surgery. 36.69% patients deemed unsuitable for resection surgery were treated with best supportive care palliatively. 57.19% patients were in ASAIII, 24.10% ASAII and 12.23% ASAIV. 46.40% patients died during the study period. Conclusion:Age on its own would not be taken as for less aggressive therapy; Careful assessment of the patient taking into consideration comorbidities, functional status and patient wishes are essential in decision making and choosing appropriate management plan. Curative surgery for colorectal carcinoma in the geriatric patients are well tolerated. Management of comorbidities preceding surgery may impact postoperative outcome.
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老年结直肠癌患者的预后
背景:老年外科患者在接受选择性和紧急手术时,术后不良结果的风险仍然增加。老年外科病人的需求往往与年轻病人有很大的不同。作为外科医生,我们在如何恰当地治疗老年病人方面面临两难。具体来说,癌症患者已经被证明接受了不适当的护理,根据他们的实际年龄而不是他们的虚弱程度,要么治疗不足,要么治疗过度。目的:评价80岁及以上结直肠癌患者的预后。方法:回顾性研究2015年1月至2019年12月在英国卢顿和邓斯特布尔大学医院治疗的所有80岁及以上结直肠癌患者。结果:研究期间诊断为结直肠癌的患者278例,男性143例,女性135例,比例为1:1.05。年龄从80岁到101岁不等。54.31%的患者接受手术干预。15.10%出现术后并发症。36.69%认为不适合切除手术的患者采用姑息性最佳支持治疗。ASAIII占57.19%,ASAII占24.10%,ASAIV占12.23%。46.40%的患者在研究期间死亡。结论:年龄本身不能作为减量治疗的依据;仔细评估患者,考虑合并症,功能状态和患者的意愿是必不可少的决策和选择适当的管理计划。老年结直肠癌患者的根治性手术具有良好的耐受性。术前合并症的处理可能影响术后结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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