Bacteriological Profile and Antimicrobial Resistance Pattern in Surgical Site Infection in a Tertiary Care Hospital, Central Nepal

B. Jha, S. Gautam, J. Sharma, Manisha Sharma
{"title":"Bacteriological Profile and Antimicrobial Resistance Pattern in Surgical Site Infection in a Tertiary Care Hospital, Central Nepal","authors":"B. Jha, S. Gautam, J. Sharma, Manisha Sharma","doi":"10.3126/mjsbh.v20i2.33399","DOIUrl":null,"url":null,"abstract":"Introduction: Surgical site wound infections (SSI) are the third most commonly reported nosocomial infection and they account for approximately a quarter of all nosocomial infections. Apart from bacterial contamination of wound, various patient and environment related factors play a role in development and outcome of SSI. The present study is undertaken to study the frequency of SSI and the antimicrobial resistance pattern of the causative organisms isolated. \nMethods: This cross-sectional prospective study was carried out over a period of one year. A total of 245 pus samples from suspected cases of surgical site infections were processed for gram staining, culture, biochemical identification tests and antimicrobial susceptibility testing using standard microbiological protocol. Data was analysed using software word version SPSS 19. \nResults: The overall frequency of SSI was 13.87%. Most common isolates were staphylococcus aureus and Escherichia coli. All four staph aureus strains were resistant to penicillin and cefixime but were 100% sensitive to vancomycin and cloxacillin. Two out of four stains were methicillin resistant Staph. aureus (MRSA). Another concern in recent time is the isolation of acinetobacter from surgical wounds. \nConclusions: Preoperative antibiotics, reduced hospital stay and proper control of co-morbidities decrease the incidence of post-operative infections. Marked resistance of isolates to commonly used antibiotics signifies the need for judicious and rational use of these drugs to prevent the emergence of antibiotic resistant strains.","PeriodicalId":33963,"journal":{"name":"Medical Journal of Shree Birendra Hospital","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Shree Birendra Hospital","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/mjsbh.v20i2.33399","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

Introduction: Surgical site wound infections (SSI) are the third most commonly reported nosocomial infection and they account for approximately a quarter of all nosocomial infections. Apart from bacterial contamination of wound, various patient and environment related factors play a role in development and outcome of SSI. The present study is undertaken to study the frequency of SSI and the antimicrobial resistance pattern of the causative organisms isolated. Methods: This cross-sectional prospective study was carried out over a period of one year. A total of 245 pus samples from suspected cases of surgical site infections were processed for gram staining, culture, biochemical identification tests and antimicrobial susceptibility testing using standard microbiological protocol. Data was analysed using software word version SPSS 19. Results: The overall frequency of SSI was 13.87%. Most common isolates were staphylococcus aureus and Escherichia coli. All four staph aureus strains were resistant to penicillin and cefixime but were 100% sensitive to vancomycin and cloxacillin. Two out of four stains were methicillin resistant Staph. aureus (MRSA). Another concern in recent time is the isolation of acinetobacter from surgical wounds. Conclusions: Preoperative antibiotics, reduced hospital stay and proper control of co-morbidities decrease the incidence of post-operative infections. Marked resistance of isolates to commonly used antibiotics signifies the need for judicious and rational use of these drugs to prevent the emergence of antibiotic resistant strains.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
尼泊尔中部一家三级护理医院手术部位感染的细菌学特征和抗微生物药物耐药性模式
手术部位伤口感染(SSI)是第三大最常报告的医院感染,约占所有医院感染的四分之一。除了伤口的细菌污染外,各种患者和环境相关因素在SSI的发生和结局中起着重要作用。目前的研究是为了研究SSI的频率和分离的致病生物的抗菌素耐药性模式。方法:这项横断面前瞻性研究在一年的时间内进行。对疑似手术部位感染病例的245份脓液标本进行革兰氏染色、培养、生化鉴定和药敏试验,采用标准微生物学方案。采用SPSS 19软件对数据进行分析。结果:SSI总发生率为13.87%。最常见的分离物是金黄色葡萄球菌和大肠杆菌。4株金黄色葡萄球菌均对青霉素和头孢克肟耐药,但对万古霉素和氯西林100%敏感。4个样本中有2个是耐甲氧西林葡萄球菌。葡萄球菌(MRSA)。最近的另一个问题是手术伤口中不动杆菌的分离。结论:术前应用抗生素、减少住院时间和合理控制合并症可降低术后感染的发生率。分离株对常用抗生素的明显耐药性表明需要明智和合理地使用这些药物,以防止出现耐药菌株。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
25
审稿时长
12 weeks
期刊最新文献
A Retrospective study to Analyze the Outcomes of Paediatric Pyeloplasty in Poorly Functioning Kidneys Visual Function at High Altitude in Nepal A Case of Hydropyometra Secondary to Vaginal Atresia: A Case Report Endovascular Management of a Rare Case of a True Facial Artery Aneurysm: A Case Report Spectrum of Neurological cases in OPD of Tertiary Paediatric care Center of Nepal
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1