I. Lozada‐Martínez, M. G. Ortega-Sierra, María Milagros Daza-Vega, Leidy Natalia Cárdenas-Hormiga, Jorge Eduardo Contreras-Saldarriaga, Carlos Eduardo Garcia-Moron, J. Serna-Trejos, Jorge Alberto Nuñez-Gamez, Daniela Gómez-Murillo, Mary Elena Rosero-Burgos, L. Moscote-Salazar
{"title":"Basic considerations on growth hormone deficiency in traumatic brain injury","authors":"I. Lozada‐Martínez, M. G. Ortega-Sierra, María Milagros Daza-Vega, Leidy Natalia Cárdenas-Hormiga, Jorge Eduardo Contreras-Saldarriaga, Carlos Eduardo Garcia-Moron, J. Serna-Trejos, Jorge Alberto Nuñez-Gamez, Daniela Gómez-Murillo, Mary Elena Rosero-Burgos, L. Moscote-Salazar","doi":"10.33962/roneuro-2021-082","DOIUrl":null,"url":null,"abstract":"Growth hormone is responsible for stimulating the growth and differentiation of cells of various tissues and cell types contribute to protein synthesis and the mobilization of fatty acids. At the nervous system level, it stimulates the regeneration of neurons, astrocytes, endothelial cells, oligodendrocytes, and even neuronal myelination. Traumatic brain injuries can alter the secretion of this hormone, due to the deformation of brain tissue and the alteration of neurometabolism by the subsequent ischemia. Knowing the basic aspects of pituitary disorders in this type of patient allows early identification and management to avoid complications","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Neurosurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33962/roneuro-2021-082","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Growth hormone is responsible for stimulating the growth and differentiation of cells of various tissues and cell types contribute to protein synthesis and the mobilization of fatty acids. At the nervous system level, it stimulates the regeneration of neurons, astrocytes, endothelial cells, oligodendrocytes, and even neuronal myelination. Traumatic brain injuries can alter the secretion of this hormone, due to the deformation of brain tissue and the alteration of neurometabolism by the subsequent ischemia. Knowing the basic aspects of pituitary disorders in this type of patient allows early identification and management to avoid complications