Basic considerations on growth hormone deficiency in traumatic brain injury

I. Lozada‐Martínez, M. G. Ortega-Sierra, María Milagros Daza-Vega, Leidy Natalia Cárdenas-Hormiga, Jorge Eduardo Contreras-Saldarriaga, Carlos Eduardo Garcia-Moron, J. Serna-Trejos, Jorge Alberto Nuñez-Gamez, Daniela Gómez-Murillo, Mary Elena Rosero-Burgos, L. Moscote-Salazar
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Abstract

Growth hormone is responsible for stimulating the growth and differentiation of cells of various tissues and cell types contribute to protein synthesis and the mobilization of fatty acids. At the nervous system level, it stimulates the regeneration of neurons, astrocytes, endothelial cells, oligodendrocytes, and even neuronal myelination. Traumatic brain injuries can alter the secretion of this hormone, due to the deformation of brain tissue and the alteration of neurometabolism by the subsequent ischemia. Knowing the basic aspects of pituitary disorders in this type of patient allows early identification and management to avoid complications
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创伤性脑损伤生长激素缺乏的基本考虑
生长激素负责刺激各种组织细胞的生长和分化,细胞类型有助于蛋白质合成和脂肪酸的动员。在神经系统水平上,它刺激神经元、星形胶质细胞、内皮细胞、少突胶质细胞的再生,甚至神经元髓鞘形成。创伤性脑损伤由于脑组织的变形和随后的缺血导致神经代谢的改变,可以改变这种激素的分泌。了解这类患者的垂体疾病的基本方面可以早期识别和管理,以避免并发症
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