{"title":"Wenlafaksyna XR, zastosowanie kliniczne większych dawek (> 150 mg)","authors":"Paweł Mierzejewski","doi":"10.5603/psych.2020.0014","DOIUrl":null,"url":null,"abstract":"This paper discusses the dual serotonergic-noradrenergic mechanism of action of venlafaxine, its indications for use, and dosage. Special attention was paid to the clinical application of higher doses of the drug, above 150 mg in the treatment of depression and anxiety disorders. Venlafaxine is one of the most effective antidepressants. The maximum recommended dose is 225 mg/day for anxiety disorders and 375 mg/day for major depression. The use of higher doses of the drug allows to take full advantage of its dual mechanism of action and improve its effectiveness.","PeriodicalId":39960,"journal":{"name":"Psychiatria","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychiatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5603/psych.2020.0014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
This paper discusses the dual serotonergic-noradrenergic mechanism of action of venlafaxine, its indications for use, and dosage. Special attention was paid to the clinical application of higher doses of the drug, above 150 mg in the treatment of depression and anxiety disorders. Venlafaxine is one of the most effective antidepressants. The maximum recommended dose is 225 mg/day for anxiety disorders and 375 mg/day for major depression. The use of higher doses of the drug allows to take full advantage of its dual mechanism of action and improve its effectiveness.
期刊介绍：
"Psychiatry" is a quaternary journal addressed to professionals coming from all branches of psychiatry practicing in both hospital and outpatients departments. "Psychiatry" issues original articles, reviews, case reports, commentaries, and translated articles from leading journals in the field of psychiatry. The papers are reviewed by the members of the editorial board. "Psychiatry" also publishes the practice guidelines in sexology. Psychopharmacotherapy is the main field of interests of the quatrernary.
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