It is time to work on the extension of body growth and reproductive stages.

IF 2.2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Rejuvenation research Pub Date : 2022-03-16 DOI:10.1089/rej.2022.0017
W. Gu
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引用次数: 4

Abstract

There are three major changes for the human lifespan in the past half decade: the decreased age of sexual maturity, slight increase in age of menopause/ andropause, and a trend of increase in life expectancy. The ages of puberty and menopause are the transitions in life stages, such that early puberty leads to loss and late menopause leads to gain the lifespan. So far, the strategies for increased lifespan have been largely focused on the post-reproductive stage. These approaches are challenging and may at some point reach a plateau. It might be interesting to expand this focus to potentially delaying the puberty and extending the period of body growth, which might yield longer reproductive stages as well as the longer and healthier lifespan.
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是时候研究身体生长和生殖阶段的延长了。
在过去的五年里,人类的寿命有三个主要变化:性成熟年龄下降,更年期/更年期年龄略有增加,预期寿命有增加的趋势。青春期和更年期是人生阶段的过渡,因此青春期早期会导致损失,更年期晚期会延长寿命。到目前为止,延长寿命的策略主要集中在生殖后阶段。这些方法具有挑战性,可能在某个时候达到平稳期。将这一重点扩展到可能延迟青春期和延长身体生长期可能会很有趣,这可能会产生更长的生殖阶段以及更长、更健康的寿命。
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来源期刊
Rejuvenation research
Rejuvenation research 医学-老年医学
CiteScore
4.50
自引率
0.00%
发文量
41
审稿时长
3 months
期刊介绍: Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence. Rejuvenation Research coverage includes: Cell immortalization and senescence Pluripotent stem cells DNA damage/repair Gene targeting, gene therapy, and genomics Growth factors and nutrient supply/sensing Immunosenescence Comparative biology of aging Tissue engineering Late-life pathologies (cardiovascular, neurodegenerative and others) Public policy and social context.
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