Konstantinos P. Chatzipapas, N. Tran, M. Dordevic, Sara Zivkovic, S. Zein, W. Shin, D. Sakata, Nathanael Lampe, Jeremy M. C. Brown, A. Ristic-Fira, I. Petrović, I. Kyriakou, D. Emfietzoglou, S. Guatelli, S. Incerti
{"title":"Simulation of DNA damage using Geant4‐DNA: an overview of the “molecularDNA” example application","authors":"Konstantinos P. Chatzipapas, N. Tran, M. Dordevic, Sara Zivkovic, S. Zein, W. Shin, D. Sakata, Nathanael Lampe, Jeremy M. C. Brown, A. Ristic-Fira, I. Petrović, I. Kyriakou, D. Emfietzoglou, S. Guatelli, S. Incerti","doi":"10.1002/pro6.1186","DOIUrl":null,"url":null,"abstract":"The scientific community shows great interest in the study of DNA damage induction, DNA damage repair, and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4‐DNA example application, named “molecularDNA”, publicly released in the 11.1 version of Geant4 (December 2022).","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Precision Radiation Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/pro6.1186","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 5
Abstract
The scientific community shows great interest in the study of DNA damage induction, DNA damage repair, and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4‐DNA example application, named “molecularDNA”, publicly released in the 11.1 version of Geant4 (December 2022).