Simulation of DNA damage using Geant4‐DNA: an overview of the “molecularDNA” example application

Q4 Medicine Precision Radiation Oncology Pub Date : 2022-10-04 DOI:10.1002/pro6.1186
Konstantinos P. Chatzipapas, N. Tran, M. Dordevic, Sara Zivkovic, S. Zein, W. Shin, D. Sakata, Nathanael Lampe, Jeremy M. C. Brown, A. Ristic-Fira, I. Petrović, I. Kyriakou, D. Emfietzoglou, S. Guatelli, S. Incerti
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引用次数: 5

Abstract

The scientific community shows great interest in the study of DNA damage induction, DNA damage repair, and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4‐DNA example application, named “molecularDNA”, publicly released in the 11.1 version of Geant4 (December 2022).
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使用Geant4‐DNA模拟DNA损伤:“分子DNA”示例应用概述
科学界对DNA损伤诱导、DNA损伤修复以及暴露于电离辐射后对细胞和细胞系统的生物学影响的研究表现出极大的兴趣。到目前为止,已经提出了几种使用蒙特卡罗模拟来研究这些机制的计算机方法。本研究概述了Geant4-DNA的示例应用程序,名为“分子DNA”,在Geant4的11.1版本中公开发布(2022年12月)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Precision Radiation Oncology
Precision Radiation Oncology Medicine-Oncology
CiteScore
1.20
自引率
0.00%
发文量
32
审稿时长
13 weeks
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