Role of bacteriocholia in development of infectious complications of pancreaticoduodenal resection

Abstract

The incidence of infectious complications after pancreaticoduodenal resection remains significant. High frequency of bacteriocholia in this category of patients is a result of preoperative biliary drainage. The role of bacteriocholia in the development of surgical site infection and the methods of exposure to it are yet to be studied. The authors presented the analysis of Russian and foreign literature and considered the role of bacteriocholia in the development of surgical site infection after pancreaticoduodenal resection. Bacteriocholia appears to be one of the most significant factors in the surgical site infection after this kind of resection. Bacterial cultures in the intraoperative bile sample and the surgical microbiome are represented by pathogens resistant to standard drugs used for perioperative antibiotic prophylaxis. In order to decrease the incidence of surgical site infections after the pancreaticoduodenal resection it is essential to continue searching for the methods of exposure to bacteriocholia including revision of the approaches to perioperative administration of antibacterial agents.