Lang Lin , Jie Yang , Yan Yang , Hui Zhi , Xin Hu , Dongkun Chai , Yunjie Liu , Xiaojun Shen , Jie Wang , Yunqi Song , Aimei Zeng , Xinyu Li , Haibo Feng
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引用次数: 8
Abstract
In this study, the effects of phosphorylation of Radix Cyathula officinalis polysaccharide (RCPS) on its immunological properties were evaluated using broiler chickens immunized with Newcastle disease vaccine (NDV). The results suggested that phosphorylated RCPS (pRCPS) could enhance antibody titers against NDV vaccination, improve the indexes of thymus, the bursa of fabricius and spleen, and up-regulate IL-2, IL-4, IL-5, IL-6, IL-10, and IFN-γ. Overall, pRCPS could significantly improve cellular and humoral immune responses in broiler chickens immunized with NDV and thus represents a useful immunotherapeutic agent.
期刊介绍：
The Journal of Carbohydrate Chemistry serves as an international forum for research advances involving the chemistry and biology of carbohydrates. The following aspects are considered to fall within the scope of this journal:
-novel synthetic methods involving carbohydrates, oligosaccharides, and glycoconjugates-
the use of chemical methods to address aspects of glycobiology-
spectroscopic and crystallographic structure studies of carbohydrates-
computational and molecular modeling studies-
physicochemical studies involving carbohydrates and the chemistry and biochemistry of carbohydrate polymers.
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