Asymptomatic, Chronic Type-A Dissection of a Large Ascending Thoracic Aortic Aneurysm in a Young Patient

R. T. Tung, J. Heyns, Lynne A. Dryer, Barbara Eitutis
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引用次数: 1

Abstract

INTRODUCTION Incidence of thoracic aortic dissection (TAD) in the general population is very low, ranging from 2.6 3.5 cases per 100,000 persons per year, but it is associated with a high rate of mortality and morbidity.1-3 Based on the nature of its onset and anatomical location, TAD is classified as either acute or chronic Stanford type-A dissection involving the ascending aorta and type-B distal to the left subclavian artery.4,5 Acute type-A dissection is highly lethal with a 30-day mortality of 50% compared to 10% of type B.2 Most acute TAD patients presented with a sudden onset of severe chest, abdominal, or back pain, but 6.4% of them may have painless dissection.6 The majority of patients with TAD were older with a mean age of 63 years while only 7% of them were less than 40 years of age.7 Common predisposing factors for TAD are hypertension, atherosclerosis, and a history of cardiac surgery2, while in young patients they are more likely Marfan’s syndrome, bicuspid aortic valve, and prior aortic surgery.7 We report a case of a healthy, young male veteran who presented with asymptomatic, chronic type-A dissection of a large aortic aneurysm, complicated by severe aortic regurgitation (AR). Several physical signs characteristic of chronic, severe AR were found in this patient.
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一名年轻患者的无症状慢性A型大型上行胸主动脉瘤夹层
引言胸主动脉夹层(TAD)在普通人群中的发病率非常低,每年每100000人中有2.6-3.5例,但它与高死亡率和发病率有关。1-3根据其发病性质和解剖位置,TAD分为急性或慢性斯坦福A型夹层,涉及升主动脉和左锁骨下动脉远端的B型。4,5急性A型夹层具有高度致死性,30天死亡率为50%,而B.2型的死亡率为10%。大多数急性TAD患者突然出现严重的胸部、腹部或背部疼痛,但6.4%的患者可能患有无痛性夹层。6大多数TAD患者年龄较大,平均年龄为63岁,而只有7%的患者年龄小于40岁。7 TAD的常见易感因素是高血压、动脉粥样硬化和心脏手术史2,而在年轻患者中,他们更可能患上马凡氏综合征、,和既往主动脉手术。7我们报告了一例健康的年轻男性退伍军人,他表现为无症状的慢性a型大主动脉瘤夹层,并伴有严重主动脉反流(AR)。在这名患者身上发现了一些以慢性、严重AR为特征的体征。
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