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引用次数: 0
CLN3结合溶酶体清除甘油磷脂
CLN3是一种溶酶体跨膜蛋白，已知CLN3突变的缺失会导致一种幼年致死性神经退行性溶酶体储存障碍（LSD），称为Batten病。在最近发表在《自然》杂志上的一项研究中，Laqtom等人报道了CLN3通过甘油二酯（GPD）的溶酶体外排清除溶酶体中甘油磷脂的新功能，不仅建立了对Batten病更深入的机制理解，还表明了CLN3-GPD在这类神经退行性LSD中的诊断和治疗潜力。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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