Neurologic Manifestation in Children with Coronavirus Disease 2019 at Prof. Dr. I.G.N.G Ngoerah Tertiary Hospital

Michelle Husin, Dewi Sutriani, Mahalini, Gusti Ngurah, Made Suwarba, Ni Putu, Siadi Purniti, I. B. Subanada, Ksenija Bogoeva-Kostovska
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Abstract

AIM: The objective of the study is to describe neurologic manifestation in children with coronavirus disease-2019 (COVID-19) at Prof. Dr. I.G.N.G Ngoerah Hospital. METHODS: This was a retrospective descriptive study using the medical record with a total sampling of children with confirmed COVID-19 that  manifests neurologic symptoms. Exclusion criteria were pre-existing neurologic comorbidities and incomplete medical records. RESULTS: From March 2020 to December 2021, from 308 children with confirmed cases of COVID-19, 106 had neurologic symptoms, 17 were  excluded (16 pre-existing comorbidities, and 1 incomplete medical record), and total samples were 89 (28.8%) from inpatient and outpatient. Most children were male (57.3%) with a median age of 13 years. Most symptoms found were anosmia (73%), followed by a decrease in consciousness (19.1%) and seizure (10.1%). Children with anosmia median age were 14 years. There were 84 (94.3%) children with specific neurological symptoms  (encephalopathy, seizures, and anosmia) and 5 (5.7%) with non-specific neurological symptoms (headache). CONCLUSION: There were 28.8% confirmed cases of COVID-19 with a neurologic manifestation, and most symptoms found were anosmia (73%).
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Ngoerah三级医院2019年冠状病毒病儿童的神经系统表现
目的:本研究的目的是描述I.G.N.G Ngoerah Hospital教授博士2019冠状病毒病(新冠肺炎)儿童的神经表现。排除标准是预先存在的神经系统合并症和不完整的医疗记录。结果:从2020年3月至2021年12月,在308名新冠肺炎确诊病例的儿童中,106名儿童出现神经系统症状,17名被排除在外(16例预先存在的合并症,1份医疗记录不完整),住院和门诊样本总数为89份(28.8%)。大多数儿童为男性(57.3%),中位年龄为13岁。发现的大多数症状是嗅觉缺失(73%),其次是意识下降(19.1%)和癫痫发作(10.1%)。嗅觉缺失儿童的中位年龄为14岁。有84名(94.3%)儿童出现特定的神经系统症状(脑病、癫痫发作和嗅觉缺失),5名(5.7%)儿童出现非特异性的神经系统疾病症状(头痛)。
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期刊介绍: Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, i­n­formation on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.
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