Antibacterial Effectiveness of Calcium Hydroxide Combined with Cresotin against Enterococcus faecalis

IF 0.1 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Archives of Orofacial Science Pub Date : 2021-09-22 DOI:10.21315/aos2021.16.s1.3
A. Aprilia, Belinda Kusuma, Istien Wardani
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Abstract

The goal of endodontic treatment is to prevent and control of pulp and periradicular infections. Calcium hydroxide has a beneficial biological property as an intracanal medicament and can be combined with cresotin to disinfect bacteria in root canals, especially Enterococcus faecalis (E. faecalis) which is the most frequently isolated strain in the root canals. The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide, cresotin, and combination calcium hydroxide and cresotin (Ca[OH]2+Cresotin, 1:1 and 1:2) against E. faecalis. Antibacterial activity was determined by the agar diffusion method. The test medicaments were placed inside the hole that made in the inoculated agar medium. The zone of growth inhibition was measured and recorded after incubation for each plate, and the result was analysed statistically with ANOVA. The in vitro antimicrobial effects of combination calcium hydroxide and cresotin (Ca[OH]2+Cresotin, 1:2) has more prominent antimicrobial activity than others, and calcium hydroxide is more effective than cresotin alone. The antimicrobial activity of combined calcium hydroxide and cresotin is more effective in killing E. faecalis in comparison to the other treatments.
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氢氧化钙与克索汀联合应用对粪肠球菌的抗菌效果
根管治疗的目的是预防和控制牙髓和根周感染。氢氧化钙作为一种管内药物具有良好的生物学特性,可与甲酚素联合对根管内细菌进行消毒,尤其是粪肠球菌(E. faecalis)是根管内最常见的分离菌株。研究了氢氧化钙、cresotin以及氢氧化钙与cresotin的组合(Ca[OH]2+ cresotin, 1:1和1:2)对粪肠球菌的体外抑菌活性。采用琼脂扩散法测定其抑菌活性。试验药物放置在接种琼脂培养基上的孔内。每个培养皿孵育后测量并记录生长抑制区,并用方差分析对结果进行统计学分析。氢氧化钙与cresotin (Ca[OH]2+ cresotin, 1:2)联合使用的体外抑菌效果较其他组合更突出,且氢氧化钙比单用cresotin更有效。与其他处理相比,氢氧化钙与cresotin复合处理对粪肠杆菌的杀灭效果更好。
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来源期刊
Archives of Orofacial Science
Archives of Orofacial Science DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
0.30
自引率
50.00%
发文量
27
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