Effects of three-month feeding high-fat diets with different
fatty acid composition on kidney histology and expression
of genes related to cellular stress and water-electrolyte
homeostasis in mice
A. Wypych, A. Dunisławska, M. Grabowska, K. Michałek, M. Ożgo, K. Liput, A. Herosimczyk, E. Polawska, M. Pierzchała, A. Lepczynski
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引用次数: 1
Abstract
. The Western diet, which is typically high in saturated fatty acids (SFAs) and low in n-3 polyunsaturated fatty acids (PUFAs), has been identified as a factor contributing to the growing obesity rate. Long-term consumption of high-fat diets (HFDs) has also been associated with increased risk of chronic kidney disease. Therefore, we hypothesized that different fatty acids composition in HFDs would differentially affect renal microstructure and expression pattern of selected genes. Swiss-Webster male mice (n = 24) were fed a standard chow for mice (STD
期刊介绍:
Journal of Animal and Feed Sciences (JAFS, J. Anim. Feed Sci.) has been published by the Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland) since 1991. It is a continuation of the Polish-language journal Roczniki Nauk Rolniczych. Seria B, Zootechniczna published by the Polish Academy of Sciences since 1969.
JAFS is an international scientific journal published quarterly, about 40 papers per year including original papers, short communications and occasionally reviews. All papers are peer-reviewed and related to basic and applied researches in the field of animal breeding and genetics, physiology of nutrition, animal feeding, feed technology and food preservation. The journal distinguishes the multidisciplinary nature of physiological and nutritional sciences and so includes papers specialized in all fields connected with animal well-being, including molecular and cell biology and the emerging area of genetics.