Role of food allergy in otitis media with effusion

Wessam Fouad, Sayed Makhemaer, Hala Abd Mohamed, A. Awwad
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Abstract

Background and aim The role of food allergy (FA) in chronic otitis media with effusion (OME) is argumentative. New proof from cellular biology and immunology clarifies the essentials of allergic responses and permits exact diagnosis more than before for allergies and inflammatory disease. We aimed to detect the occurrence of FA in patients with chronic OME. Patients and methods This a prospective, cohort randomized controlled study that was conducted at Al Azhar University Hospital, Otorhinolaryngology Department, on 40 patients divided into two groups: patient group included 20 patients with OME, and control group included 20 patients without any medical problems about FA or OME. The prevalence of FA was detected by skin prick test and assessment of serum immunoglobulin E and eosinophil count. Results There were highly statistically significant correlations between increase in the total serum immunoglobulin E and eosinophil count and developing OME (P<0.00); however, there were no statistically significant correlations between age and developing OME (P<0.396). Conclusion The possibility of association and the contribution of FA should be kept in mind in OME cases.
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食物过敏在渗出性中耳炎中的作用
背景与目的食物过敏(FA)在慢性渗出性中耳炎(OME)中的作用是有争议的。细胞生物学和免疫学的新证据阐明了过敏反应的本质,并比以前更准确地诊断过敏和炎症性疾病。我们旨在检测FA在慢性OME患者中的发生情况。患者和方法这是一项前瞻性、队列随机对照研究,在爱资哈尔大学医院耳鼻喉科对40名患者进行,分为两组:患者组包括20名OME患者,对照组包括20例没有任何FA或OME医疗问题的患者。通过皮肤点刺试验和血清免疫球蛋白E和嗜酸性粒细胞计数评估FA的患病率。结果血清总免疫球蛋白E和嗜酸性粒细胞计数的增加与OME的发生具有高度统计学意义(P<0.00);但年龄与OME的发生无统计学意义(P<0.396)。
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审稿时长
34 weeks
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