The Safe Use of Rituximab In The Management of ANCA-Associated Vasculitis In A Patient With Suspicious Renal Cyst – A Case Report

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Abstract

ANCA- Associated Vasculitis (AAV) is a multi-system immune small vessel vasculitis. The use of traditional immunosuppressive agents in the management of ANCA vasculitis is known to increase baseline susceptibility to malignancy [1]. Renal cyst is a commonly encountered incidental finding in clinical practice. Although most cysts found are benign, the identification of complex cysts warrants further diagnostic investigation to exclude a neoplastic process. To shed light on this complex area, the Bosniak system has provided a framework for the classification of cystic renal lesions. The system defines five categories of renal lesions based on radiological features seen on CT or MRI, to stratify the lesions associated risk of malignancy [2].
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利妥昔单抗在治疗可疑肾囊肿患者ANCA相关血管炎中的安全应用——一例报告
ANCA相关血管炎(AAV)是一种多系统免疫性小血管血管炎。已知在ANCA血管炎的治疗中使用传统免疫抑制剂会增加对恶性肿瘤的基线易感性[1]。肾囊肿是临床上常见的偶然发现。尽管发现的大多数囊肿是良性的,但复杂囊肿的鉴定需要进一步的诊断研究,以排除肿瘤过程。为了阐明这一复杂区域,波斯尼亚系统为囊性肾脏病变的分类提供了一个框架。该系统根据CT或MRI上的放射学特征定义了五类肾脏病变,以对病变相关的恶性肿瘤风险进行分层[2]。
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