Health Related Quality of Life Following Coronary Revascularization: A Prospective Cross-sectional Study

M. Salah, Hussein Wamdha, M. Yagoub
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Abstract

Introduction Coronary Artery Bypass Grafting (CABG) and percutaneous coronary intervention (PCI) are invasive options for managing patients with coronary artery disease (CAD). CABG was first introduced in 1964 and it has been firmly recognized since then as a key surgical intervention for patients with intractable angina pectoris despite medications and myocardial infarction [1,2]. Percutaneous transluminal coronary angioplasty (PTCA) or percutaneous coronary intervention (PCI) established in 1979 by Andreas Gruentzig in Switzerland to treat stenotic coronary lesions of coronary arteries, the procedure then progressed technically and introduced devices like stents which improve not only long-term patency of treated lesions but also the prognosis of patients [3,4]. With the use of both revascularization methods (CABG and PCI), the relief of symptom and survival rates have increased [5]. The relative efficacy, benefits and risks of the two procedures have been compared in several studies [6-12]. In the latest published European and American guidelines, both CABG and PCI are accepted revascularization methods to reduce mortality and improve morbidity [13,14].
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冠状动脉血运重建术后健康相关生活质量的前瞻性横断面研究
冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)是治疗冠状动脉疾病(CAD)患者的侵入性选择。冠状动脉搭桥术于1964年首次被引入,自那时起,冠状动脉搭桥术就被坚定地认为是治疗顽固性心绞痛患者的关键手术干预手段,尽管有药物治疗和心肌梗死[1,2]。1979年,瑞士的Andreas Gruentzig创立了经皮腔内冠状动脉成形术(Percutaneous transl腔内冠状动脉成形术,PTCA)或经皮冠状动脉介入治疗(Percutaneous coronary intervention, PCI),用于治疗冠状动脉狭窄病变。随后,该手术在技术上取得了进步,引入了支架等装置,不仅改善了被治疗病变的长期通畅,而且改善了患者的预后[3,4]。同时采用CABG和PCI两种血运重建方法,症状的缓解和生存率均有所提高。多项研究比较了这两种手术的相对疗效、益处和风险[6-12]。在最新出版的欧美指南中,CABG和PCI都是公认的血运重建术,以降低死亡率和提高发病率[13,14]。
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