Assessment of Possible Link of Intestinal Microbiota and Type 2 Diabetes Mellitus

G. Simeon, Arikekpar Ibemologi, Dienize George Cameron
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Abstract

Introduction: This study assessed the role of gut bacteria in the development of type 2 Diabetes Mellitus. Methodology: Using bacteria cultural method, microbial species were isolated from feacal materials, identified and quantitated through application of genomic spectrophotometric systems with a quantitation of some marker biochemical parameters for Diabetes. Result: We observed a concentration of firmicutes, bacteriodetes, protecbacteria and bifidobacterium with Escherichia coli population predominating. Biochemical parameters reveal a 3-fold raised value for some bromakers in type 2 diabetes. At a confidence interval of 95% paired sample test results gave significant differences for all tested pairs. Conclusion: Result suggests that microbiomes have the potential to alter the gut environment and cause changes that promote the development of type 2 diabetes.
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肠道菌群与2型糖尿病可能联系的评估
本研究评估了肠道细菌在2型糖尿病发展中的作用。方法:采用细菌培养法,从粪便材料中分离微生物种类,应用基因组分光光度系统对糖尿病的一些标志物生化参数进行定量鉴定和定量。结果:观察到厚壁菌门、抑菌门、保护菌和双歧杆菌的浓度,以大肠杆菌为主。生化参数显示,一些bromaker在2型糖尿病中的价值提高了3倍。在95%的置信区间内,成对样本检验结果对所有被检验的对都有显著差异。结论:结果提示微生物组有可能改变肠道环境并引起促进2型糖尿病发展的变化。
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