{"title":"Editorial - Do odontogenic tumors occur even in the dental clinic?","authors":"N. A. Nunes","doi":"10.15600/2238-1236/fol.v29n1p2","DOIUrl":null,"url":null,"abstract":"Among the intra-osseous lesions, we find the root cysts very frequently. Due to the inflammatory process and involvement of the pulp, it is known to dentists. However, when think about odontogenic tumors, the frequent, painless odontoma often discovered on routine radiographs may come to mind. Easy to diagnose when compound.1 But what about other tumors derived from dental tissues? Ameloblastoma is a benign and relatively common neoplasm (10 to 49% of odontogenic tumors)1,2,3, originated of odontogenic epithelium, it may involve soft tissues (peripheral ameloblastoma) 4 or bone tissue of the maxilla and mandible, with a higher incidence in the mandible , with variable forms and histopathological classification, observed in young in the second and third decades of life or later.1,2,3 The radiographic and imaging aspects they may be unilocular or multilocular, resembling cystic lesion5,6 or multiple radiolucent areas2. Ameloblastomas present several histopathological types and the diagnosis allows more or less invasive treatments, since they tend to recur frequently7. From the damage produced to extensive surgeries and the need for reconstruction, it is noted that there are also cases of its correlation with squamous cell carcinomas in the mandible6, the behavior of ameloblastomas is considered more or less aggressive7. The diagnosis of this type of odontogenic tumor is histopathological and immunoistiquimic, whith positivity identified for CK19 and p634; BRAF V600E mutation RAS, FGFR2 or SMO7. Histopathological variations for World Health Organization, it is solid or multicystic and unicystic5,7. Subtypes as plexiform, desmoplastic, follicular and acanthomatous are described. Unictics type have a less aggressive behavior3. Jaw injuries are more frequent than in the maxilla. Recurrences are associated with mutations, which are more frequent in this region7. RefeRências","PeriodicalId":77785,"journal":{"name":"Revista da Faculdade de Odontologia de Lins","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista da Faculdade de Odontologia de Lins","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15600/2238-1236/fol.v29n1p2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Among the intra-osseous lesions, we find the root cysts very frequently. Due to the inflammatory process and involvement of the pulp, it is known to dentists. However, when think about odontogenic tumors, the frequent, painless odontoma often discovered on routine radiographs may come to mind. Easy to diagnose when compound.1 But what about other tumors derived from dental tissues? Ameloblastoma is a benign and relatively common neoplasm (10 to 49% of odontogenic tumors)1,2,3, originated of odontogenic epithelium, it may involve soft tissues (peripheral ameloblastoma) 4 or bone tissue of the maxilla and mandible, with a higher incidence in the mandible , with variable forms and histopathological classification, observed in young in the second and third decades of life or later.1,2,3 The radiographic and imaging aspects they may be unilocular or multilocular, resembling cystic lesion5,6 or multiple radiolucent areas2. Ameloblastomas present several histopathological types and the diagnosis allows more or less invasive treatments, since they tend to recur frequently7. From the damage produced to extensive surgeries and the need for reconstruction, it is noted that there are also cases of its correlation with squamous cell carcinomas in the mandible6, the behavior of ameloblastomas is considered more or less aggressive7. The diagnosis of this type of odontogenic tumor is histopathological and immunoistiquimic, whith positivity identified for CK19 and p634; BRAF V600E mutation RAS, FGFR2 or SMO7. Histopathological variations for World Health Organization, it is solid or multicystic and unicystic5,7. Subtypes as plexiform, desmoplastic, follicular and acanthomatous are described. Unictics type have a less aggressive behavior3. Jaw injuries are more frequent than in the maxilla. Recurrences are associated with mutations, which are more frequent in this region7. RefeRências