An immunity-structured SEIRS epidemic model with variable infectivity and spatial heterogeneity

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-05-22 DOI:10.15388/namc.2023.28.32230
V. Skakauskas, A. Ambrazevičius
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Abstract

A mathematical model is proposed for the spread of an epidemic disease of agedependent infectivity through an asexual population with spatial heterogeneity, assuming that some individuals recover from the disease with temporary immunity, another part recover with permanent immunity, and the last part recover with no immunity. The demographic changes such as births and deaths due to natural causes and the chronological age of individuals are not taken into account. The model is based on a system of partial integro-differential equations including a differential equation to describe the evolution of individuals who have recovered with temporary immunity. The existence and uniqueness of the globally defined solution is proved, and its long-time behaviour is studied.
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具有可变传染性和空间异质性的免疫结构SEIRS流行病模型
提出了一种年龄依赖性传染病在具有空间异质性的无性种群中传播的数学模型,假设部分个体具有暂时免疫,一部分个体具有永久免疫,最后一部分个体无免疫。人口变化,如自然原因造成的出生和死亡以及个人的实际年龄没有考虑在内。该模型基于一个偏积分微分方程系统,其中包括一个微分方程,用于描述恢复暂时免疫的个体的进化。证明了全局定义解的存在唯一性,并研究了其长时性。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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