{"title":"Organosilicon polymer for the release of antimicrobial drugs","authors":"S. Sarraj, M. Szymiczek","doi":"10.14314/polimery.2022.4.2","DOIUrl":null,"url":null,"abstract":"An organosilicon polymer was developed for the release of antimicrobial drugs. The influence of the drug itraconazole (Itrax) on polymer properties such as density, hardness, rebound resilience, tensile strength, accelerated aging, structure and antifungal activity was investigated. There were slight changes in physicochemical properties and significant deterioration of mechanical ones. The evaluation of the fungicidal activity showed time-limited antifungal properties.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polimery","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.14314/polimery.2022.4.2","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
An organosilicon polymer was developed for the release of antimicrobial drugs. The influence of the drug itraconazole (Itrax) on polymer properties such as density, hardness, rebound resilience, tensile strength, accelerated aging, structure and antifungal activity was investigated. There were slight changes in physicochemical properties and significant deterioration of mechanical ones. The evaluation of the fungicidal activity showed time-limited antifungal properties.
期刊介绍:
The "Polimery" journal, of international circulation, is publishing peerreviewed scientific and technical research papers covering polymer science and technology in the field of polymers, rubbers, chemical fibres and paints. The range of topics covered are raw materials, polymer synthesis, processing and applications of polymers. Apart from scientific and technical research papers the monthly includes technical and commercial information such as reports from fairs and exhibitions as well as home, world and technical news.
“Polimery "- an international journal covering the following topics: polymers, rubber, chemical fibres and paints.
The Journal is addressed to scientists, managers and engineering staff of universities, Polish Academy of Sciences, R&D institutions, industry, specializing in polymer chemistry, physical chemistry, technology and processing. “Polimery” publishes original, reviewed research, scientific and technology papers in the field of polymer synthesis, analysis, technology and modification, processing, properties, applications and recycling.