Results of Two-Years Mammographic Screening in the Kaluga Region

K. S. Drzhevetskaya, G. P. Korzhenkova
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Abstract

Objective: approbation of the project of mass breast cancer mammographic screening in the Kaluga Region.Material and methods. From April 2018 to December 2019, screening mammography was performed in 35,439 women aged from 38 to 93 years (mean age 57.33 ± 8.07 years). The study was carried out on mobile mammography complexes assembled on Russian KamAZ vehicles with Russian-made equipment from Amiko company. Mammography was performed in frontal and oblique projections. BI-RADS ACR international classification was used to standardize the identified changes and assess the sensitivity and specificity of the study method.Results. Out of the total number of women examined, pathological changes (BI-RADS IV–V) were assumed according to mammography data in 778 (2.2%) cases, of which 700 (1.98%) patients appealed to an oncological institution. Benign processes were found in 394 (1.11%) patients, breast cancer in 164 (0.46%). Without verification of the diagnosis, 137 (0.39%) patients remained under the supervision of oncologists. Distribution of detected tumors by stages for 2 years of observation: stage 0 – 7, stage 1 – 73, stage 2 – 56, stage 3 – 13, stage 4 – 3. The stage was not set in 4 cases. The total number of those examined with verification of the diagnosis in the oncological institution was 596. The proportion of correct diagnoses was 94%. The total number of diagnostic errors that would occur in the absence of a true double scan accounted for 36 (6%) cases.Conclusion. The proposed screening method makes it possible to increase the breast cancer detection in the early preclinical stages of the disease, to provide the available diagnostics for the population due to mobile mammography complexes, and to speed up the process of diagnostics and further hospitalization for examination and necessary treatment according to the disease stage in a specialized oncological institution.
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卡卢加地区两年乳房x光检查结果
目的:批准卡卢加地区大规模乳腺癌乳房x线摄影筛查项目。材料和方法。2018年4月至2019年12月,对35439名年龄38 ~ 93岁(平均年龄57.33±8.07岁)的女性进行了乳房x光筛查。这项研究是在俄罗斯KamAZ车辆上组装的移动乳房x线照相术综合体上进行的,这些设备是由Amiko公司制造的俄罗斯设备。在额位和斜位投影处进行乳房x光检查。采用BI-RADS ACR国际分级对所发现的变化进行标准化,并评估研究方法的敏感性和特异性。在接受检查的妇女总数中,778例(2.2%)的病例根据乳房x光检查数据推定病理改变(BI-RADS IV-V),其中700例(1.98%)的患者向肿瘤机构求助。良性病变394例(1.11%),乳腺癌164例(0.46%)。在诊断未经证实的情况下,137例(0.39%)患者仍在肿瘤学家的监督下。2年观察发现肿瘤分期分布:0 ~ 7期、1 ~ 73期、2 ~ 56期、3 ~ 13期、4 ~ 3期。4例未定台。在肿瘤机构检查并确认诊断的总人数为596人。正诊率为94%。在没有真正的双重扫描的情况下,诊断错误的总数占36例(6%)。所提出的筛查方法可以在疾病的早期临床前阶段增加乳腺癌的检测,通过移动乳房x线照相术为人群提供可用的诊断,并加快诊断过程,根据疾病阶段进一步住院检查和必要的治疗到专门的肿瘤机构。
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审稿时长
36 weeks
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