{"title":"Hepatit B Virus DNA Flare During In Vitro Fertilization","authors":"Muge Toygar-Deniz, S. Akhan","doi":"10.36519/kd.2022.4211","DOIUrl":null,"url":null,"abstract":"Potent antivirals are used for the treatment of hepatitis B infection. A 38-year-old female patient whose hepatit B virus (HBV) viral load was suppressed under tenofovir disoproxil fumarate treatment but had a viral flare during in vitro fertilization (IVF) treatment is presented. Although HBV DNA was negative continuously in the controls, an increase in HBV DNA was observed during IVF treatment. Hepatitis B has been isolated from many extrahepatic tissues. Ovarian stimulation is likely to increase viral replication. Therefore, it is essential to check HBV DNA periodically to prevent vertical transmission.","PeriodicalId":44309,"journal":{"name":"Klimik Journal","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Klimik Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36519/kd.2022.4211","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Potent antivirals are used for the treatment of hepatitis B infection. A 38-year-old female patient whose hepatit B virus (HBV) viral load was suppressed under tenofovir disoproxil fumarate treatment but had a viral flare during in vitro fertilization (IVF) treatment is presented. Although HBV DNA was negative continuously in the controls, an increase in HBV DNA was observed during IVF treatment. Hepatitis B has been isolated from many extrahepatic tissues. Ovarian stimulation is likely to increase viral replication. Therefore, it is essential to check HBV DNA periodically to prevent vertical transmission.
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